Venom-induced blood disturbances by palearctic viperid snakes, and their relative neutralization by antivenoms and enzyme-inhibitors

A Chowdhury, CN Zdenek, MR Lewin, R Carter… - Frontiers in …, 2021 - frontiersin.org
Palearctic vipers are medically significant snakes in the genera Daboia, Macrovipera,
Montivipera, and Vipera which occur throughout Europe, Central Asia, Near and Middle …

Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics

JM Gutiérrez, G Solano, D Pla, M Herrera, Á Segura… - Toxicon, 2013 - Elsevier
The assessment of the capacity of antivenoms to neutralize the lethal activity of snake
venoms is the gold standard in the preclinical analysis of antivenom efficacy, and is routinely …

Ammodytoxin: a window into understanding presynaptic toxicity of secreted phospholipases A2 and more

I Križaj - Toxicon, 2011 - Elsevier
Venoms of many snakes induce neurotoxic effects in animals. Among the first inducers of
such symptoms to be identified was a group of proteins that belongs to the phospholipase …

Influence of post-starvation extraction time and prey-specific diet in Tityus serrulatus scorpion venom composition and hyaluronidase activity

MB Pucca, FG Amorim, FA Cerni, KCF Bordon… - Toxicon, 2014 - Elsevier
The role of diet in venom composition has been a topic of intense research interest. This
work presents evidence that the variation in the venom composition from the scorpion Tityus …

Vipera ammodytes bites treated with antivenom ViperaTAb: a case series with pharmacokinetic evaluation

M Brvar, T Kurtović, D Grenc, M Lang Balija… - Clinical …, 2017 - Taylor & Francis
Context: In clinical practice it is difficult to differentiate between V. berus and V. ammodytes
venomous bites. In the past this was not a concern, but due to the current shortage in …

Biological Activities and Proteomic Profile of the Venom of Vipera ursinii ssp., a very Rare Karst Viper from Croatia

M Lang Balija, A Leonardi, M Brgles, D Sviben… - Toxins, 2020 - mdpi.com
The karst viper (Vipera ursinii ssp.) favours high-mountain dry grasslands in southern and
south-eastern Croatia. It is medically less important than other Vipera species, because of its …

Preclinical assessment of a new polyvalent antivenom (Inoserp europe) against several species of the subfamily viperinae

A García-Arredondo, M Martínez, A Calderón… - Toxins, 2019 - mdpi.com
The European continent is inhabited by medically important venomous Viperinae snakes.
Vipera ammodytes, Vipera berus, and Vipera aspis cause the greatest public health …

Protein structure of the venom in nine species of snake: from bio-compounds to possible healing agents

RT Cristina, R Kocsis, C Tulcan, E Alexa… - Brazilian Journal of …, 2020 - SciELO Brasil
Due to its various structures in bio-compounds, snake venom is the indisputable result of
evolutionary stages of molecules with an increasingly complex structure, high specificity …

Comparison of cytotoxicity methods for studying Vipera ammodytes venom and the anticytotoxic potency of antivenom

I Lukic, V Blagojevic, R Minic, S Ivanovic… - … European Journal of …, 2024 - termedia.pl
Results: The IC 50 value of V. ammodytes venom obtained by these methods was very
similar, while the EC 50 values differed significantly. Conclusions: We concluded that the …

Paraspecificity of Vipera a. ammodytes-specific antivenom towards Montivipera raddei and Macrovipera lebetina obtusa venoms

T Kurtović, ML Balija, N Ayvazyan, B Halassy - Toxicon, 2014 - Elsevier
Antivenom raised against the venom of nose-horned viper, Vipera ammodytes (V. a.)
ammodytes (European viper venom antiserum, Zagreb antivenom), contains neutralising …