The production of black pigments in bacteria was discovered more than a century ago and
related to tyrosine metabolism. However, their diverse biological roles and the control of …

Alkaptonuria is a rare inborn error of metabolism caused by the deficiency of homogentisate
1, 2-dioxygenase activity. The consequent homogentisic acid (HGA) accumulation in body …

Alkaptonuria (AKU) is a rare autosomal recessive disorder that results from the deficient
activity of homogentisate 1, 2-dioxygenase and leads to increased levels of homogentisic …

The aromatic amino acid tyrosine is an essential precursor for the synthesis of
catecholamines, including L-DOPA, tyramine, and dopamine. A number of metabolic …

Exogenous ochronosis (EO) can be an unintended psychologically troubling condition for
patients who are already being treated for longer-term hyperpigmentation disorders such as …

Melanins are a class of conjugated biopolymers with varying compositions and functions,
which have a variety of potential medical and technical applications. Here, this work …

Soybean (Glycine max) is a major plant source of protein and oil and produces important
secondary metabolites beneficial for human health. As a tool for gene function discovery and …

A luminescent nanozyme was designed and synthesized for the enzymatic luminescence
assay of tyrosine. This luminescent nanozyme is composed of luminescent Tb 3+, catalytic …

Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which
causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The …

Alkaptonuria (AKU) is an ultrarare autosomal recessive disorder (MIM 203500) that is
caused byby a complex set of mutations in homogentisate 1, 2-dioxygenasegene and …