Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Cancer heterogeneity has posed a great challenge to traditional cancer treatment, with the
reappearance of cancer heterogeneity of inter and intra patients being especially critical …

The functional status of innate immune cells is a considerable determinant of effective
antitumor immune response. However, the triple-negative breast cancer tumor …

In addition to individual imaging techniques, the combination and integration of several
imaging techniques, so-called multimodal imaging, can provide large amounts of …

Nanobubbles (NBs) have recently garnered widespread attention for their potential use as
dual diagnostic and therapeutic agents. Similar to their micron-sized relatives …

Drug-loaded nanoscale cavitation agents, called nanodroplets, are an attractive solution to
enhance and localize drug delivery, offering increased stability and prolonged half-life in …

Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …

Introduction Delivering sufficient therapeutics at the target site without off-target effects is a
major goal of drug delivery technology innovation. Among the established methods …

Colorectal cancer causes the third most common type of malignant tumors with high
morbidity and mortality. Chemotherapy is currently one of the most effective and common …

Lipid-shelled nanobubbles (NBs) are emerging as potential dual diagnostic and therapeutic
agents. Similar to their micron-scale counterparts, microbubbles (1–10 μm), they can act as …