Psychedelic therapies reconsidered: compounds, clinical indications, and cautious optimism

JM Mitchell, BT Anderson - Neuropsychopharmacology, 2024 - nature.com
The clinical investigation of psychedelic medicines has blossomed over the last 5 years.
Data from a Phase 3 industry trial and a multicenter Phase 2 industry trial, in addition to …

Ayahuasca's therapeutic potential: What we know–and what not

LO Maia, D Daldegan-Bueno, I Wießner… - European …, 2023 - Elsevier
The therapeutic potential of the psychedelic brew ayahuasca has been investigated in
preclinical and clinical studies. Currently, the most consistent evidence refers to depression …

[HTML][HTML] Adverse effects of ayahuasca: Results from the Global Ayahuasca Survey

JC Bouso, Ó Andión, JJ Sarris… - PLOS Global Public …, 2022 - journals.plos.org
Introduction Ayahuasca is a plant-based decoction native to Amazonia, where it has a long
history of use in traditional medicine. Contemporary ritual use of ayahuasca has been …

Therapeutic effect of an ayahuasca analogue in clinically depressed patients: a longitudinal observational study

K Van Oorsouw, SW Toennes, JG Ramaekers - Psychopharmacology, 2022 - Springer
Rationale Studies have suggested mental health improvements following the use of the
psychotropic plant concoction ayahuasca in non-clinical and clinical samples. Objectives …

The use of classic hallucinogens/psychedelics in a therapeutic context: Healthcare policy opportunities and challenges

RG Dos Santos, JC Bouso, JM Rocha… - … and healthcare policy, 2021 - Taylor & Francis
Psychedelics or serotonergic hallucinogens are a group of substances that share the
agonism of serotonergic 5-HT2A receptors as their main mechanism of action. Its main …

Potential safety, benefits, and influence of the placebo effect in microdosing psychedelic drugs: A systematic review

G Ona, JC Bouso - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Microdosing psychedelic drugs—that is, taking sub-behavioral doses of lysergic acid
diethylamide (LSD) or psilocybin—is a growing practice in Western societies. Taken mainly …

Persisting effects of ayahuasca on empathy, creative thinking, decentering, personality, and well-being

MK Kiraga, NL Mason, MV Uthaug… - Frontiers in …, 2021 - frontiersin.org
Background: Naturalistic and placebo-controlled studies have suggested that ayahuasca, a
traditional Amazonian beverage, could be helpful in the treatment of psychopathologies like …

N, N‐dimethyltryptamine and Amazonian ayahuasca plant medicine

E James, J Keppler, TL Robertshaw… - Human …, 2022 - Wiley Online Library
Objective Reports have indicated possible uses of ayahuasca for the treatment of conditions
including depression, addictions, post‐traumatic stress disorder, anxiety and specific …

Ceremonial ayahuasca in amazonian retreats—mental health and epigenetic outcomes from a six-month naturalistic study

SGD Ruffell, N Netzband, WF Tsang, M Davies… - Frontiers in …, 2021 - frontiersin.org
Ayahuasca is a natural psychoactive brew, used in traditional ceremonies in the Amazon
basin. Recent research has indicated that ayahuasca is pharmacologically safe and its use …

The Shipibo ceremonial use of ayahuasca to promote well-being: an observational study

D Gonzalez, J Cantillo, I Perez, M Carvalho… - Frontiers in …, 2021 - frontiersin.org
Promoting well-being is one of the main goals to improve health in the world. We examined
the well-being and quality of life over the course of one year in a sample that participated in …