[HTML][HTML] Epigenetic modulations of immune cells: from normal development to tumor progression

Y Xu, Z He, J Du, Z Chen, JWM Creemers… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
The dysfunction of immune cell development often impairs immunological homeostasis, thus
causing various human diseases. Accumulating evidence shows that the development of …

Role and regulators of N6-methyladenosine (m6A) RNA methylation in inflammatory subtypes of asthma: a comprehensive review

G Gao, YQ Hao, C Wang, P Gao - Frontiers in Pharmacology, 2024 - frontiersin.org
Asthma is a common chronic inflammatory disease of the lungs and airway, yet its
inflammatory subtypes and potential pathogenesis have not been completely elucidated and …

N6-methyladenosine RNA methylation, a new hallmark of metabolic reprogramming in the immune microenvironment

X Li, L Peng, X Yang, J Luo, J Wang, K Mou… - Frontiers in …, 2024 - frontiersin.org
N6-methyladenosine is one of the most common and reversible post-transcriptional
modifications in eukaryotes, and it is involved in alternative splicing and RNA transcription …

[HTML][HTML] Transcriptomic landscapes of STING-mediated DNA-sensing reveal cellular response heterogeneity

LZ Kong, IH Jang, C Wang, SY Lee, SM Kim… - International Journal of …, 2024 - Elsevier
Transfection of plasmid DNA (pDNA) encoding target genes is a routine tool in gene function
studies and therapeutic applications. However, nucleic acid-sensing-mediated innate …

[HTML][HTML] Abnormal changes in metabolites caused by m6A methylation modification: The leading factors that induce the formation of immunosuppressive tumor …

L Zhao, J Guo, S Xu, M Duan, B Liu, H Zhao… - Journal of Advanced …, 2024 - Elsevier
Abstract Background N6-methyladenosine (m 6 A) RNA methylation modifications have
been widely implicated in the metabolic reprogramming of various cell types within the tumor …

[HTML][HTML] Demethylases in tumors and the tumor microenvironment: Key modifiers of N6-methyladenosine methylation

J Guo, L Zhao, M Duan, Z Yang, H Zhao, B Liu… - Biomedicine & …, 2024 - Elsevier
RNA methylation modifications are widespread in eukaryotes and prokaryotes, with N 6-
methyladenosine (m 6 A) the most common among them. Demethylases, including Fat mass …

N6-methyladenosine (m6A) modification in Natural immune cell-mediated inflammatory diseases

Y Teng, J Yi, J Chen, L Yang - Journal of Innate Immunity, 2023 - karger.com
The post-transcriptional N6-methyladenosine (m6A) modification of RNA influences stability,
transport, and translation with implications for various physiological and pathological …

The role of m6A Modification in the risk prediction and Notch1 pathway of Alzheimer's disease

Y Qiao, Y Mei, M Xia, D Luo, L Gao - iScience, 2024 - cell.com
Summary N6-methyladenosine (m6A) methylation and abnormal immune responses are
implicated in neurodegenerative diseases, yet their relationship in Alzheimer's Disease (AD) …

Regulation and application of m6A modification in tumor immunity

Q Xiong, Y Zhang, Y Zheng, Q Zhu - Science China Life Sciences, 2024 - Springer
The m 6 A modification is an RNA modification that impacts various processes of RNA
molecules, including transcription, splicing, stability, and translation. Recently, researchers …

N6-methyladenosine (m6A) modification in inflammation: a bibliometric analysis and literature review

Z Li, Y Lao, R Yan, X Guan, Y Bai, F Li, Z Dong - PeerJ, 2024 - peerj.com
Abstract N6-methyladenosine (m6A) is the most abundant internal messenger RNA
modification in eukaryotes, influencing various physiological and pathological processes by …