Myosin motors power movements on actin filaments, whereas dynein and kinesin motors
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …

Eukaryotic cilia and flagella, including primary cilia and sensory cilia, are highly conserved
organelles that project from the surfaces of many cells. The assembly and maintenance of …

Life implies movement. Most forms of movement in the living world are powered by tiny
protein machines known as molecular motors. Among the best known are motors that use …

The atomic force microscope (AFM) has a unique capability of allowing the high-resolution
imaging of biological samples on substratum surfaces in physiological solutions. Recent …

Cytoplasmic dynein has long been thought to be responsible for retrograde axonal transport.
As the number of cellular roles for this multifunctional protein has expanded, the complexity …

It is now clear that transport on microtubules by dynein and kinesin family motors has an
important if not critical role in the replication and spread of many different viruses …

We introduce the technique of FIONA, fluorescence imaging with one nanometer accuracy.
This is a fluorescence technique that is able to localize the position of a single dye within∼ 1 …

Cytoplasmic dyneins, the principal microtubule minus-end-directed motor proteins of the
cell, are involved in many essential cellular processes. The major form of this enzyme is a …

Myosin V (myoV), a processive cargo transporter, has arguably been the most well-studied
unconventional myosin of the past decade. Considerable structural information is available …

The myosin holoenzyme is a multimeric protein complex consisting of heavy chains and light
chains. Myosin light chains are calmodulin family members which are crucially involved in …