Biofilms in diabetic foot ulcers: impact, risk factors and control strategies

AC Afonso, D Oliveira, MJ Saavedra, A Borges… - International journal of …, 2021 - mdpi.com
Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …

The insights of microbes' roles in wound healing: A comprehensive review

T Maheswary, AA Nurul, MB Fauzi - Pharmaceutics, 2021 - mdpi.com
A diverse range of normal flora populates the human skin and numbers are relatively
different between individuals and parts of the skin. Humans and normal flora have formed a …

Therapeutic potential of antimicrobial peptides in polymicrobial biofilm-associated infections

G Batoni, G Maisetta, S Esin - International Journal of Molecular Sciences, 2021 - mdpi.com
It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …

Lights and shadows on the therapeutic use of antimicrobial peptides

D Bellotti, M Remelli - Molecules, 2022 - mdpi.com
The emergence of antimicrobial-resistant infections is still a major concern for public health
worldwide. The number of pathogenic microorganisms capable of resisting common …

Friends or enemies? The complicated relationship between Pseudomonas aeruginosa and Staphylococcus aureus

DBY Yung, KJ Sircombe, D Pletzer - Molecular Microbiology, 2021 - Wiley Online Library
Abstract Pseudomonas aeruginosa (Pa) and Staphylococcus aureus (Sa) are opportunistic
pathogens that are most commonly co‐isolated from chronic wounds and the sputum of …

Lung antimicrobial proteins and peptides: From host defense to therapeutic strategies

YP Di, JM Kuhn, ML Mangoni - Physiological Reviews, 2024 - journals.physiology.org
Representing severe morbidity and mortality globally, respiratory infections associated with
chronic respiratory diseases, including complicated pneumonia, asthma, interstitial lung …

Advances in antimicrobial peptide discovery via machine learning and delivery via nanotechnology

A Sowers, G Wang, M Xing, B Li - Microorganisms, 2023 - mdpi.com
Antimicrobial peptides (AMPs) have been investigated for their potential use as an
alternative to antibiotics due to the increased demand for new antimicrobial agents. AMPs …

Multiple potential strategies for the application of nisin and derivatives

F Khan, P Singh, AS Joshi, N Tabassum… - Critical Reviews in …, 2023 - Taylor & Francis
Nisin is a naturally occurring bioactive small peptide produced by Lactococcus lactis subsp.
lactis and belongs to the Type A (I) lantibiotics. Due to its potent antimicrobial activity, it has …

[HTML][HTML] Tiger 17 and pexiganan as antimicrobial and hemostatic boosters of cellulose acetate-containing poly (vinyl alcohol) electrospun mats for potential wound …

MA Teixeira, JC Antunes, CL Seabra, SD Tohidi… - International Journal of …, 2022 - Elsevier
In this research, we propose to engineer a nanostructured mat that can simultaneously kill
bacteria and promote an environment conducive to healing for prospective wound care …

Engineered cationic antimicrobial peptides (eCAPs) to combat multidrug-resistant bacteria

B Deslouches, RC Montelaro, KL Urish, YP Di - Pharmaceutics, 2020 - mdpi.com
The increasing rate of antibiotic resistance constitutes a global health crisis. Antimicrobial
peptides (AMPs) have the property to selectively kill bacteria regardless of resistance to …