The rapid emergence of antifungal-resistant human-pathogenic fungi

SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

Candida auris Genetics and Emergence

A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …

Candida auris: Epidemiology, biology, antifungal resistance, and virulence

H Du, J Bing, T Hu, CL Ennis, CJ Nobile… - PLoS …, 2020 - journals.plos.org
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida
auris is becoming a worldwide public health threat that has been attracting considerable …

Threats posed by the fungal kingdom to humans, wildlife, and agriculture

MC Fisher, SJ Gurr, CA Cuomo, DS Blehert, H Jin… - MBio, 2020 - Am Soc Microbiol
The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with
respect to its profound impact on global health, biodiversity, ecology, agriculture …

Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

SR Lockhart, KA Etienne, S Vallabhaneni… - Clinical Infectious …, 2017 - academic.oup.com
Background. Candida auris, a multidrug-resistant yeast that causes invasive infections, was
first described in 2009 in Japan and has since been reported from several countries …

Diagnosis and treatment of invasive candidiasis

N Barantsevich, E Barantsevich - Antibiotics, 2022 - mdpi.com
Candida species, belonging to commensal microbial communities in humans, cause
opportunistic infections in individuals with impaired immunity. Pathogens encountered in …

Candida auris: a review of the literature

A Jeffery-Smith, SK Taori, S Schelenz… - Clinical microbiology …, 2018 - Am Soc Microbiol
The emerging pathogen Candida auris has been associated with nosocomial outbreaks on
five continents. Genetic analysis indicates the simultaneous emergence of separate clades …

Tracing the evolutionary history and global expansion of Candida auris using population genomic analyses

NA Chow, JF Muñoz, L Gade, EL Berkow, X Li… - MBio, 2020 - Am Soc Microbiol
Candida auris has emerged globally as a multidrug-resistant yeast that can spread via
nosocomial transmission. An initial phylogenetic study of isolates from Japan, India …

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

A Chowdhary, C Sharma, JF Meis - PLOS pathogens, 2017 - journals.plos.org
Candidiasis, which includes both superficial infections and invasive disease, is the most
common cause of fungal infection worldwide. Candida bloodstream infections (BSI) cause …

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and …

A Chowdhary, A Prakash, C Sharma… - Journal of …, 2018 - academic.oup.com
Background Candida auris has emerged globally as an MDR nosocomial pathogen in ICU
patients. Objectives We studied the antifungal susceptibility of C. auris isolates (n= 350) from …