The no-reflow phenomenon refers to the observation that when an organ is made ischemic
by occlusion of a large artery supplying it, restoration of patency in that artery does not …

The past two decades have witnessed an explosive growth of knowledge regarding
postischemic myocardial dysfunction or myocardial “stunning.” The purpose of this review is …

Therapeutic strategies to protect the ischemic myocardium have been studied extensively.
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …

In experimental studies in the dog, total proximal coronary artery occlusions of up to 15
minutes result in reversible injury, meaning that the myocytes survive this insult. The 15 …

BACKGROUND We investigated myocardial perfusion dynamics after thrombolysis and its
clinical implications. METHODS AND RESULTS We studied 39 patients with acute anterior …

Recent epidemiologic studies show that increased levels of air pollutants are positively
associated with cardiovascular morbidity and mortality. Inhalation of air pollutants affects …

To achieve early and complete reperfusion of the myocardium in acute coronary syndromes
is the daily challenge for every physician in clinical cardiology. However, restoration of …

Oxygen free radicals are known to be generated during periods of ischemia followed by
reperfusion. There is still some controversy, however, concerning the use of electron …

Postischemic reperfusion may profoundly alter cardiac function. Principal mediators of this
phenomenon are oxygen radicals and neutrophils. Upon reflow, oxygen radicals are …

Both animal models of experimental myocardial infarction and clinical studies on reperfusion
therapy for acute myocardial infarction have provided evidence of impaired tissue perfusion …