As the primary microtubule-organizing center in animal cells, centrosomes regulate
microtubule cytoskeleton to support various cellular behaviors. They also serve as the base …

In ascomycete fungi, sexual spores, termed ascospores, are formed after meiosis.
Ascospore formation is an unusual cell division in which daughter cells are created within …

Synthetic tools for the control of protein function are valuable for biomedical research to
characterize cellular functions of essential proteins or if a rapid switch in protein activity is …

Correct intracellular distribution of proteins is critical for the function of eukaryotic cells.
Certain proteins are targeted to more than one cellular compartment, eg to mitochondria and …

Control of cellular events by optogenetic tools is a powerful approach to manipulate cellular
functions in a minimally invasive manner. A common problem posed by the application of …

Wild Saccharomyces cerevisiae strains are typically diploid. When faced with glucose and
nitrogen limitation they can undergo meiosis and sporulate. Diploids can also enter a …

During exit from meiosis II, cells undergo several structural rearrangements, including
disassembly of the meiosis II spindles and cytokinesis. Each of these changes is regulated …

Spirochetes of the genus Treponema are surprisingly abundant in termite guts, where they
play an important role in reductive acetogenesis. Although they occur in all termites …

Peroxisomes are organelles with crucial functions in oxidative metabolism. To correctly
target to peroxisomes, proteins require specialized targeting signals. A mystery in the field is …

Recent metagenomic studies have identified numerous lineages of hydrogen-dependent,
obligately methyl-reducing methanogens. Yet only a few representatives have been isolated …