Vimentin: Regulation and pathogenesis
Vimentin, an abundant cytoplasmic intermediate filament protein, is recognized for its
important role in stabilizing intracellular structure. Vimentin has been recognized for its …
important role in stabilizing intracellular structure. Vimentin has been recognized for its …
Vimentin diversity in health and disease
F Danielsson, MKK Peterson, H Caldeira Araújo… - Cells, 2018 - mdpi.com
Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …
Vimentin as a multifaceted player and potential therapeutic target in viral infections
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …
functions, and therefore in basic cellular processes such as cell division and migration …
Microparticle traction force microscopy reveals subcellular force exertion patterns in immune cell–target interactions
Force exertion is an integral part of cellular behavior. Traction force microscopy (TFM) has
been instrumental for studying such forces, providing spatial force measurements at …
been instrumental for studying such forces, providing spatial force measurements at …
Mechanical and non‐mechanical functions of filamentous and non‐filamentous vimentin
Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …
Omics-based approaches to guide the design of biomaterials
Recent developments in biomedical engineering have focused on designing smart and bio-
responsive materials. However, a critical step in designing this next generation of …
responsive materials. However, a critical step in designing this next generation of …
Strong triaxial coupling and anomalous Poisson effect in collagen networks
While cells within tissues generate and sense 3D states of strain, the current understanding
of the mechanics of fibrous extracellular matrices (ECMs) stems mainly from uniaxial, biaxial …
of the mechanics of fibrous extracellular matrices (ECMs) stems mainly from uniaxial, biaxial …
Subendothelial stiffness alters endothelial cell traction force generation while exerting a minimal effect on the transcriptome
Endothelial cells respond to changes in subendothelial stiffness by altering their migration
and mechanics, but whether those responses are due to transcriptional reprogramming …
and mechanics, but whether those responses are due to transcriptional reprogramming …
Geometric constraint-triggered collagen expression mediates bacterial-host adhesion
Y Feng, S Wang, X Liu, Y Han, H Xu, X Duan… - Nature …, 2023 - nature.com
Cells living in geometrically confined microenvironments are ubiquitous in various
physiological processes, eg, wound closure. However, it remains unclear whether and how …
physiological processes, eg, wound closure. However, it remains unclear whether and how …
Causal contributors to tissue stiffness and clinical relevance in urology
L Martinez-Vidal, V Murdica, C Venegoni… - Communications …, 2021 - nature.com
Mechanomedicine is an emerging field focused on characterizing mechanical changes in
cells and tissues coupled with a specific disease. Understanding the mechanical cues that …
cells and tissues coupled with a specific disease. Understanding the mechanical cues that …