Vimentin: Regulation and pathogenesis

D Paulin, A Lilienbaum, S Kardjian, O Agbulut, Z Li - Biochimie, 2022 - Elsevier
Vimentin, an abundant cytoplasmic intermediate filament protein, is recognized for its
important role in stabilizing intracellular structure. Vimentin has been recognized for its …

Vimentin diversity in health and disease

F Danielsson, MKK Peterson, H Caldeira Araújo… - Cells, 2018 - mdpi.com
Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …

Vimentin as a multifaceted player and potential therapeutic target in viral infections

I Ramos, K Stamatakis, CL Oeste… - International journal of …, 2020 - mdpi.com
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …

Microparticle traction force microscopy reveals subcellular force exertion patterns in immune cell–target interactions

D Vorselen, Y Wang, MM de Jesus, PK Shah… - Nature …, 2020 - nature.com
Force exertion is an integral part of cellular behavior. Traction force microscopy (TFM) has
been instrumental for studying such forces, providing spatial force measurements at …

Mechanical and non‐mechanical functions of filamentous and non‐filamentous vimentin

AE Patteson, A Vahabikashi, RD Goldman… - …, 2020 - Wiley Online Library
Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …

Omics-based approaches to guide the design of biomaterials

AL Kersey, TU Nguyen, B Nayak, I Singh, AK Gaharwar - Materials Today, 2023 - Elsevier
Recent developments in biomedical engineering have focused on designing smart and bio-
responsive materials. However, a critical step in designing this next generation of …

Strong triaxial coupling and anomalous Poisson effect in collagen networks

E Ban, H Wang, JM Franklin… - Proceedings of the …, 2019 - National Acad Sciences
While cells within tissues generate and sense 3D states of strain, the current understanding
of the mechanics of fibrous extracellular matrices (ECMs) stems mainly from uniaxial, biaxial …

Subendothelial stiffness alters endothelial cell traction force generation while exerting a minimal effect on the transcriptome

EE Bastounis, YT Yeh, JA Theriot - Scientific reports, 2019 - nature.com
Endothelial cells respond to changes in subendothelial stiffness by altering their migration
and mechanics, but whether those responses are due to transcriptional reprogramming …

Geometric constraint-triggered collagen expression mediates bacterial-host adhesion

Y Feng, S Wang, X Liu, Y Han, H Xu, X Duan… - Nature …, 2023 - nature.com
Cells living in geometrically confined microenvironments are ubiquitous in various
physiological processes, eg, wound closure. However, it remains unclear whether and how …

Causal contributors to tissue stiffness and clinical relevance in urology

L Martinez-Vidal, V Murdica, C Venegoni… - Communications …, 2021 - nature.com
Mechanomedicine is an emerging field focused on characterizing mechanical changes in
cells and tissues coupled with a specific disease. Understanding the mechanical cues that …