Antidiabetic potential of medicinal plants and their active components
B Salehi, A Ata, N V. Anil Kumar, F Sharopov… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus is one of the major health problems in the world, the incidence and
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …
Chrysin: Perspectives on contemporary status and future possibilities as pro-health agent
M Stompor-Gorący, A Bajek-Bil, M Machaczka - Nutrients, 2021 - mdpi.com
Chrysin belongs to the group of natural polyphenols. It can be found, among others, in
honey, propolis and fruits and has a wide range of biological activities, including the …
honey, propolis and fruits and has a wide range of biological activities, including the …
Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
Molecular docking and inhibition studies of vulpinic, carnosic and usnic acids on polyol pathway enzymes
Aldose reductase (AR) and sorbitol dehydrogenase (SDH) are important enzymes of the
polyol pathway. In the current study, inhibitory effects of vulpinic acid (VA) carnosic acid (CA) …
polyol pathway. In the current study, inhibitory effects of vulpinic acid (VA) carnosic acid (CA) …
Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis
Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune
disorders and malignant diseases. However, its usage is restricted due to its severe side …
disorders and malignant diseases. However, its usage is restricted due to its severe side …
Assessment of hypolipidemic and anti‐inflammatory properties of walnut (Juglans regia) seed coat extract and modulates some metabolic enzymes activity in triton …
Atherosclerosis and cognitive impairment are both influenced by hyperlipidemia. Due to
their high margin of safety and low cost, natural chemicals have recently attracted particular …
their high margin of safety and low cost, natural chemicals have recently attracted particular …
Synthesis, biological evaluation, and in silico study of novel library sulfonates containing quinazolin‐4(3H)‐one derivatives as potential aldose reductase inhibitors
A series of novel sulfonates containing quinazolin‐4 (3 H)‐one ring derivatives was
designed to inhibit aldose reductase (ALR2, EC 1.1. 1.21). Novel quinazolinone derivatives …
designed to inhibit aldose reductase (ALR2, EC 1.1. 1.21). Novel quinazolinone derivatives …
Synthesis, biological evaluation and in silico studies of novel N-substituted phthalazine sulfonamide compounds as potent carbonic anhydrase and …
The synthesis, characterization and biological evaluation of a series of novel N-substituted
phthalazine sulfonamide (5a-l) are disclosed. Phthalazines which are nitrogen-containing …
phthalazine sulfonamide (5a-l) are disclosed. Phthalazines which are nitrogen-containing …
Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors
Alzheimer's disease (AD) is a complex, predominant, and progressive form of dementia. The
treatment of AD alters depending on the cognitive and behavioral symptoms. The utility of …
treatment of AD alters depending on the cognitive and behavioral symptoms. The utility of …
Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions
The purpose of the current study was to examine the neuroprotective effect of rutin against
colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly …
colistin-induced neurotoxicity in rats. Thirty-five male Sprague Dawley rats were randomly …