In Vivo Tumor Targeting and Image-Guided Drug Delivery with Antibody-Conjugated, Radiolabeled Mesoporous Silica Nanoparticles

F Chen, H Hong, Y Zhang, HF Valdovinos, S Shi… - ACS …, 2013 - ACS Publications
Since the first use of biocompatible mesoporous silica (mSiO2) nanoparticles as drug
delivery vehicles, in vivo tumor targeted imaging and enhanced anticancer drug delivery has …

[HTML][HTML] Iridium metal complex targeting oxidation resistance 1 protein attenuates spinal cord injury by inhibiting oxidative stress-associated reactive oxygen species

C Peng, J Luo, K Wang, J Li, Y Ma, J Li, H Yang… - Redox Biology, 2023 - Elsevier
Oxidative stress is a key factor leading to profound neurological deficits following spinal cord
injury (SCI). In this study, we present the development and potential application of an iridium …

Human adipose tissue-and umbilical cord-derived stem cells: which is a better alternative to treat spinal cord injury?

AM Liu, BL Chen, LT Yu, T Liu, LL Shi… - Neural Regeneration …, 2020 - journals.lww.com
Multiple types of stem cells have been proposed for the treatment of spinal cord injury, but
their comparative information remains elusive. In this study, a rat model of T10 contusion …

Feruloylated oligosaccharides alleviate central nervous inflammation in mice following spinal cord contusion

J Li, L Huang, L Yu, G Tao, Z Wang… - Journal of Agricultural …, 2020 - ACS Publications
As one of the empirical models of the chronic central inflammatory response, a spinal cord
injury (SCI) deteriorates the neuronal survival and results in irreversible motor and sensory …

A comparison between two laminectomy procedures in mouse spinal cord injury on Allen's animal model

H Wu, K Tong, X Liu, J Li, X Li, M Gao, W Tian… - Journal of Neuroscience …, 2022 - Elsevier
2. Materials and methods The protocols used here were reviewed and approved by the
Institutional Review Board and Ethics Committee of the Seventh Affiliated Hospital of Sun …

Establishing a mouse contusion spinal cord injury model based on a minimally invasive technique

EYY Elzat, X Fan, Z Yang, Z Yuan, Y Pang… - JoVE (Journal of …, 2022 - jove.com
Using minimally invasive methods to model spinal cord injury (SCI) can minimize behavioral
and histological differences between experimental animals, thereby improving the …

[HTML][HTML] A modified impactor for establishing a graded contusion spinal cord injury model in rats

R Yan, E Li, K Yan, Q Zhang, Y Wen… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Given the indispensable role of animal models in preclinical studies of spinal
cord injury (SCI) and the current state of available impactors, we designed a modified …

[HTML][HTML] A biomimic anti-neuroinflammatory nanoplatform for active neutrophil extracellular traps targeting and spinal cord injury therapy

C Tang, Y Jin, M Wu, F Jia, X Lu, J Li, J Wu, S Zhu… - Materials Today Bio, 2024 - Elsevier
Traumatic spinal cord injury (SCI) always leads to severe neurological deficits and
permanent damage. Neuroinflammation is a vital process of SCI and have become a …

A laser-guided spinal cord displacement injury in adult mice

X Wu, W Qu, AA Bakare, YP Zhang, CME Fry… - Journal of …, 2019 - liebertpub.com
Mouse models are unique for studying molecular mechanisms of neurotrauma because of
the availability of various genetic modified mouse lines. For spinal cord injury (SCI) …

[HTML][HTML] An in vivo duo-color method for imaging vascular dynamics following contusive spinal cord injury

C Chen, YP Zhang, Y Sun, W Xiong… - Journal of …, 2017 - pmc.ncbi.nlm.nih.gov
Spinal cord injury (SCI) causes significant vascular disruption at the site of injury. Vascular
pathology occurs immediately after SCI and continues throughout the acute injury phase. In …