Multiple myeloma is characterized by heterogeneity in clinical presentation, response to
treatment, and importantly, patient outcomes. The translocation of chromosomes 11 and 14 [t …

Cytogenetic changes in multiple myeloma (MM) have emerged as one of the most important
prognostic factors. Translocations of chromosomes 4 and 14 [t (4; 14)], chromosomes 14 and …

Abstract Translocation (11; 14) on interphase fluorescent in situ hybridization in plasma cells
is regarded as a standard risk prognostic marker in multiple myeloma based on studies …

Caucasian Americans (CA) compared with African Americans (AA) have a twofold increased
incidence of multiple myeloma (MM) and have an earlier age of diagnosis. However, there is …

Abstract The t (11; 14) translocation is among the most prevalent cytogenetic abnormalities
in multiple myeloma (MM), distinguished by its unique features and biology that have been …

Multiple myeloma (MM) is a genetically complex disease. The key myeloma-initiating
genetic events are hyperdiploidy and translocations involving the immunoglobulin heavy …

Objectives The most common translocation in multiple myeloma (MM) is t (11; 14)(q13; q32),
and its importance as prognostic factor has been controversial. The aim was to analyze its …

Simple Summary The presence of t (11; 14) in MM is a significant genetic abnormality and
plays an essential role in tailoring treatment decisions. t (11; 14) is present in 15% to 20% of …

Abstract Background The t (11; 14)(q13; 32) translocation [t (11; 14)] is present in∼ 20% of
patients with newly diagnosed multiple myeloma (NDMM), but studies examining its …

Objective To investigate the prognostic value of t (11; 14) for de novo multiple myeloma
(MM) patients in novel agent era. Methods A total of 455 patients with fluorescence in situ …