Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Antiphospholipid syndrome

G Ruiz-Irastorza, M Crowther, W Branch… - The Lancet, 2010 - thelancet.com
The antiphospholipid syndrome causes venous, arterial, and small-vessel thrombosis;
pregnancy loss; and preterm delivery for patients with severe pre-eclampsia or placental …

[HTML][HTML] Laboratory criteria for antiphospholipid syndrome: communication from the SSC of the ISTH

KMJ Devreese, TL Ortel, V Pengo, B De Laat - Journal of thrombosis and …, 2018 - Elsevier
Currently, we use the classification criteria for antiphospholipid syndrome (APS) formulated
during the consensus conference in Sapporo and revised in Sydney 1. Classification criteria …

Pathogenesis of antiphospholipid syndrome: understanding the antibodies

PL Meroni, MO Borghi, E Raschi… - Nature Reviews …, 2011 - nature.com
Antiphospholipid antibodies (aPL) are both diagnostic markers for, and pathogenic drivers
of, antiphospholipid syndrome (APS). Although the presence of aPL is a necessary pre …

Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at …

G Ruiz-Irastorza, MJ Cuadrado, I Ruiz-Arruza… - Lupus, 2011 - journals.sagepub.com
The antiphospholipid syndrome (APS) is defined by the presence of thrombosis and/or
pregnancy morbidity in combination with the persistent presence of circulating …

Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances

S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …

Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

[HTML][HTML] The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS

T McDonnell, C Wincup, I Buchholz, C Pericleous… - Blood reviews, 2020 - Elsevier
Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …

14th International Congress on Antiphospholipid Antibodies Task Force. Report on antiphospholipid syndrome laboratory diagnostics and trends

ML Bertolaccini, O Amengual, L Andreoli, T Atsumi… - Autoimmunity …, 2014 - Elsevier
Current classification criteria for definite Antiphospholipid Syndrome (APS) require the use
of three laboratory assays to detect antiphospholipid antibodies (aCL, anti-β2GPI and LA) in …

Antiphospholipid syndrome: role of vascular endothelial cells and implications for risk stratification and targeted therapeutics

MT Corban, A Duarte-Garcia, RD McBane… - Journal of the American …, 2017 - jacc.org
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …