Humans ascending to high altitude (HA) experience a reduction in arterial oxyhemoglobin
saturation and, as a result, arterial O2 content (C a O 2). As HA exposure extends, this …

Hypoxia is caused by insufficient oxygen availability for the organism leading to reduced
oxygen delivery to tissues and cells. It has been regarded as a severe threat to human …

Key points Acclimatization to hypoxia leads to a reduction in plasma volume (PV) that
restores arterial O2 content. Findings from studies investigating the mechanisms underlying …

High-altitude exposure typically reduces endothelial function, and this is modulated by
hemoconcentration resulting from plasma volume contraction. However, the specific impact …

The acute effects of active and passive ascent to high altitude on plasma volume (PV) and
rates of synthesis of albumin and fibrinogen have been examined. Measurements were …

Studies on adaptation to high altitude (HA) of 3500 m in the Himalayas were conducted in
three phases, each including 10 normal and healthy males normally resident at sea-level …

Although somewhat controversial, there is good evidence that long-distance travel in
general is a risk factor for venous thromboembolism, even in the absence of other risk …

Exposure to acute hypoxia is associated with changes in body fluid homeostasis and
plasma volume (PV). This study compared a dye dilution technique using Evans' blue (PV …

Recreation at high altitude is becoming increasingly popular. North American Rocky
Mountain recreational areas between 2000 and 3500 m elevation receive millions of visitors …

The effects of prolonged hypoxia on body water distribution was studied in four
unanesthetized adult goats (Capra lircus) at sea level and after 16 days in a hypobaric …