Antimicrobial strategies centered around reactive oxygen species–bactericidal antibiotics, photodynamic therapy, and beyond

F Vatansever, WCMA de Melo, P Avci… - FEMS microbiology …, 2013 - academic.oup.com
Reactive oxygen species (ROS) can attack a diverse range of targets to exert antimicrobial
activity, which accounts for their versatility in mediating host defense against a broad range …

Synthetic chlorins, possible surrogates for chlorophylls, prepared by derivatization of porphyrins

M Taniguchi, JS Lindsey - Chemical reviews, 2017 - ACS Publications
Chlorophylls make Earth green, are the central constituents in the engine of photosynthesis,
and not surprisingly have garnered immense attention. A chlorin, the core chromophore of a …

Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers

JM Dąbrowski, B Pucelik, A Regiel-Futyra… - Coordination Chemistry …, 2016 - Elsevier
Applications of metalloporphyrins and related molecules have been extensively pursued in
the context of photodynamic therapy of cancer (PDT) and other biomedical applications. This …

Excited state and reactive oxygen species against cancer and pathogens: a review on sonodynamic and sono‐photodynamic therapy

M Wysocki, B Czarczynska‐Goslinska… - …, 2022 - Wiley Online Library
Photodynamic and sonodynamic therapy are therapies having great potential in the
treatment of bacterial infections and cancer. Their background is associated with photo‐and …

[HTML][HTML] Photodynamic inactivation of bacteria with porphyrin derivatives: effect of charge, lipophilicity, ROS generation, and cellular uptake on their biological activity …

A Sułek, B Pucelik, M Kobielusz, A Barzowska… - International Journal of …, 2020 - mdpi.com
Resistance of microorganisms to antibiotics has led to research on various therapeutic
strategies with different mechanisms of action, including photodynamic inactivation (PDI). In …

Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection

WCMA De Melo, P Avci, MN De Oliveira… - Expert review of anti …, 2013 - Taylor & Francis
Microbial biofilms are responsible for a variety of microbial infections in different parts of the
body, such as urinary tract infections, catheter infections, middle-ear infections, gingivitis …

Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agents

N Malatesti, I Munitic, I Jurak - Biophysical reviews, 2017 - Springer
Photodynamic therapy (PDT) combines a photosensitiser, light and molecular oxygen to
induce oxidative stress that can be used to kill pathogens, cancer cells and other highly …

Photodynamic inactivation of Escherichia coli with cationic meso-tetraarylporphyrins–The charge number and charge distribution effects

C Simoes, MC Gomes, MG Neves, A Cunha, JPC Tome… - Catalysis Today, 2016 - Elsevier
The alarming level of antibiotic resistance in common pathogenic bacteria requires
alternative methods for their control. In recent years, the photodynamic inactivation of …

[HTML][HTML] Blue light disinfection in hospital infection control: advantages, drawbacks, and pitfalls

J Cabral, R Ag - Antibiotics, 2019 - mdpi.com
Hospital acquired infections (HAIs) are a serious problem that potentially affects millions of
patients whenever in contact with hospital settings. Worsening the panorama is the …

Photodegradation of organic pollutants in water by immobilized porphyrins and phthalocyanines

L Fernandez, VI Esteves, A Cunha… - Journal of Porphyrins …, 2016 - World Scientific
New methods for water treatment are required as a result from an increasing awareness in
the reduction of the pollution impact in the environment. In the perspective of the photo …