Curcumin is a polyphenol extracted from the rhizomes of the turmeric plant, Curcuma longa
which has anti-inflammatory, and anticancer properties. Chronic inflammation is associated …

Highlights•The most common reason for the failure of the cancer treatment is the evolving
drug resistance.•The ABC transporters mainly P-gp, BCRP and MRP1 are responsible for …

Female breast cancer is the world's most prevalent cancer in 2020. Chemotherapy still
remains a backbone in breast cancer therapy and is crucial in advanced and metastatic …

Dealing with cancer is of importance due to enhanced incidence rate of this life-threatening
disorder. Chemotherapy is an ideal candidate in overcoming and eradication of cancer. To …

The frequent inefficiency of conventional cancer therapies due to drug resistance, non-
targeted drug delivery, chemotherapy-associated toxic side effects turned the focus to …

Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …

Cancer stem cells (CSCs) are subpopulations of tumor masses with unique abilities in self-
renewal, stemness maintenance, drug resistance, and the promotion of cancer recurrence …

The main aim of this study was to improve the therapeutic potential of a paclitaxel (PTX) and
curcumin (CU) combination regimen using solid lipid nanoparticles (SLNs). PTX and CU …

The active form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is primarily
known as a key regulator of calcium and phosphate homeostasis. It exerts its biological …

The diarylheptanoid curcumin [(1 E, 6 E)-1, 7-bis (4-hydroxy-3-methoxyphenyl) hepta-1, 6-
diene-3, 5-dione] is one of the phenolic pigments responsible for the yellow colour of …