Strains, functions and dynamics in the expanded Human Microbiome Project

J Lloyd-Price, A Mahurkar, G Rahnavard, J Crabtree… - Nature, 2017 - nature.com
The characterization of baseline microbial and functional diversity in the human microbiome
has enabled studies of microbiome-related disease, diversity, biogeography, and molecular …

Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis

AL Byrd, C Deming, SKB Cassidy… - Science translational …, 2017 - science.org
The heterogeneous course, severity, and treatment responses among patients with atopic
dermatitis (AD; eczema) highlight the complexity of this multifactorial disease. Prior studies …

[HTML][HTML] Temporal stability of the human skin microbiome

J Oh, AL Byrd, M Park, HH Kong, JA Segre - Cell, 2016 - cell.com
Biogeography and individuality shape the structural and functional composition of the
human skin microbiome. To explore these factors' contribution to skin microbial community …

Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species

S Domingues, K Harms, WF Fricke, PJ Johnsen… - 2012 - journals.plos.org
We have investigated to what extent natural transformation acting on free DNA substrates
can facilitate transfer of mobile elements including transposons, integrons and/or gene …

Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa

A Chevallereau, BG Blasdel, J De Smet, M Monot… - PLoS …, 2016 - journals.plos.org
As interest in the therapeutic and biotechnological potentials of bacteriophages has grown,
so has value in understanding their basic biology. However, detailed knowledge of infection …

MEGAnnotator: a user-friendly pipeline for microbial genomes assembly and annotation

GA Lugli, C Milani, L Mancabelli… - FEMS microbiology …, 2016 - academic.oup.com
Genome annotation is one of the key actions that must be undertaken in order to decipher
the genetic blueprint of organisms. Thus, a correct and reliable annotation is essential in …

Evolutionary mechanisms of long-term genome diversification associated with niche partitioning in marine picocyanobacteria

H Doré, GK Farrant, U Guyet, J Haguait… - Frontiers in …, 2020 - frontiersin.org
Marine picocyanobacteria of the genera Prochlorococcus and Synechococcus are the most
abundant photosynthetic organisms on Earth, an ecological success thought to be linked to …

Comparative Metagenome-Assembled Genome Analysis of “Candidatus Lachnocurva vaginae”, Formerly Known as Bacterial Vaginosis-Associated Bacterium−1 …

JB Holm, MT France, B Ma, E McComb… - Frontiers in cellular …, 2020 - frontiersin.org
Bacterial vaginosis-associated bacterium 1 (BVAB1) is an as-yet uncultured bacterial
species found in the human vagina that belongs to the family Lachnospiraceae within the …

Genomic diversity of EPEC associated with clinical presentations of differing severity

TH Hazen, MS Donnenberg, S Panchalingam… - Nature …, 2016 - nature.com
Enteropathogenic Escherichia coli (EPEC) are diarrhoeagenic E. coli, and are a significant
cause of gastrointestinal illness among young children in developing countries. Typical …

Resolving the complexity of human skin metagenomes using single-molecule sequencing

YC Tsai, S Conlan, C Deming… - MBio, 2016 - Am Soc Microbiol
Deep metagenomic shotgun sequencing has emerged as a powerful tool to interrogate
composition and function of complex microbial communities. Computational approaches to …