Potential herb–drug interactions in the management of age-related cognitive dysfunction
MD Auxtero, S Chalante, MR Abade, R Jorge… - Pharmaceutics, 2021 - mdpi.com
Late-life mild cognitive impairment and dementia represent a significant burden on
healthcare systems and a unique challenge to medicine due to the currently limited …
healthcare systems and a unique challenge to medicine due to the currently limited …
Recent Molecular Targets and their Ligands for the Treatment of Alzheimer Disease
G Bayraktar, V Alptüzün - Current Topics in Medicinal Chemistry, 2024 - benthamdirect.com
Alzheimer's disease is a multifaceted neurodegenerative disease. Cholinergic dysfunction,
amyloid β toxicity, tauopathies, oxidative stress, neuroinflammation are among the main …
amyloid β toxicity, tauopathies, oxidative stress, neuroinflammation are among the main …
Exploring Medicinal Herbs' Therapeutic Potential and Molecular Docking Analysis for Compounds as Potential Inhibitors of Human Acetylcholinesterase in …
Background and Objectives: Alzheimer's disease (AD) stands as a pervasive
neurodegenerative ailment of global concern, necessitating a relentless pursuit of remedies …
neurodegenerative ailment of global concern, necessitating a relentless pursuit of remedies …
Novel quinazolinone Derivatives: Design, synthesis and in vivo evaluation as potential agents targeting Alzheimer disease
HK Moftah, MHA Mousa, EZ Elrazaz, AS Kamel… - Bioorganic …, 2024 - Elsevier
Since Alzheimer disease is one of the most prevalent types of dementia with a high mortality
and disability rate, so development of multi-target drugs becomes the major strategy for …
and disability rate, so development of multi-target drugs becomes the major strategy for …
[PDF][PDF] Molecular docking studies of flavonoids from Andrographis paniculata as potential acetylcholinesterase, butyrylcholinesterase and monoamine oxidase …
Neurodegenerative diseases have been characterized by loss of neuron structures as well
as their functions. This study was designed to assess molecular docking of flavonoids from …
as their functions. This study was designed to assess molecular docking of flavonoids from …
BACE1 and cholinesterase inhibitory activities of compounds from Cajanus cajan and Citrus reticulata: an in silico study
KE Adewole, AA Ishola - In Silico Pharmacology, 2021 - Springer
Alzheimer's disease (AD) is one of the major neurodegenerative diseases whose underlying
risk factors are yet to be fully understood. However, reduced cellular level of cholinesterase …
risk factors are yet to be fully understood. However, reduced cellular level of cholinesterase …
Computational studies on the cholinesterase, beta-secretase 1 (BACE1) and monoamine oxidase (MAO) inhibitory activities of endophytes-derived compounds …
Abstract Cholinesterases, beta-secretase 1 (BACE1) and monoamine oxidase (MAO) are
significant in the etiology of neurodegenerative diseases. Inhibition of these enzymes is …
significant in the etiology of neurodegenerative diseases. Inhibition of these enzymes is …
Newly synthesized 1, 2, 3-triazoles based on [1, 4]-benzoxazin-3-one: In silico evaluation of anti-inflammatory, antibacterial, antioxidant, anticancer, and antidiabetic …
D Addichi, A Farihi, N Hachimi, S Loughmari… - 2024 - researchsquare.com
Based on the significant biological activity of benzoxazines and 1, 2, 3-triazoles, we aim to
combine these active moieties to design and synthesize new compounds and evaluate their …
combine these active moieties to design and synthesize new compounds and evaluate their …
[HTML][HTML] Research of therapeutic basis of Astragalus PE intervention based on the content of matrix metalloproteinase (MMP) protein in the serum of patients with …
Z Li, J Li, M Li, A Cai, H Liu, G Miao… - Food Science and …, 2022 - SciELO Brasil
Matrix metalloproteinases have been proven to be the target of Alzheimer's disease (AD)
drugs. In this study, by monitoring the effects of different doses of Astragalus PE on the …
drugs. In this study, by monitoring the effects of different doses of Astragalus PE on the …
[PDF][PDF] Potential Herb–Drug Interactions in the Management of Age-Related Cognitive Dysfunction. Pharmaceutics 2021, 13, 124
MD Auxtero, S Chalante, MR Abade, R Jorge… - 2021 - researchgate.net
Late-life mild cognitive impairment and dementia represent a significant burden on
healthcare systems and a unique challenge to medicine due to the currently limited …
healthcare systems and a unique challenge to medicine due to the currently limited …