Challenges and emergent solutions for LC‐MS/MS based untargeted metabolomics in diseases

L Cui, H Lu, YH Lee - Mass spectrometry reviews, 2018 - Wiley Online Library
In the past decade, advances in liquid chromatography‐mass spectrometry (LC‐MS) have
revolutionized untargeted metabolomics analyses. By mining metabolomes more deeply …

PANOMICS meets germplasm

W Weckwerth, A Ghatak, A Bellaire… - Plant Biotechnology …, 2020 - Wiley Online Library
Genotyping‐by‐sequencing has enabled approaches for genomic selection to improve
yield, stress resistance and nutritional value. More and more resource studies are emerging …

The eukaryotic CO2-concentrating organelle is liquid-like and exhibits dynamic reorganization

ESF Rosenzweig, B Xu, LK Cuellar… - Cell, 2017 - cell.com
Summary Approximately 30%–40% of global CO 2 fixation occurs inside a non-membrane-
bound organelle called the pyrenoid, which is found within the chloroplasts of most …

Carbon flux through photosynthesis and central carbon metabolism show distinct patterns between algae, C3 and C4 plants

H Treves, A Küken, S Arrivault, H Ishihara, I Hoppe… - Nature Plants, 2022 - nature.com
Photosynthesis-related pathways are regarded as a promising avenue for crop
improvement. Whilst empirical studies have shown that photosynthetic efficiency is higher in …

The response of Chlamydomonas reinhardtii to nitrogen deprivation: a systems biology analysis

JJ Park, H Wang, M Gargouri, RR Deshpande… - The Plant …, 2015 - Wiley Online Library
Drastic alteration in macronutrients causes large changes in gene expression in the
photosynthetic unicellular alga Chlamydomonas reinhardtii. Preliminary data suggested that …

Algal and aquatic plant carbon concentrating mechanisms in relation to environmental change

JA Raven, M Giordano, J Beardall… - Photosynthesis Research, 2011 - Springer
Carbon dioxide concentrating mechanisms (also known as inorganic carbon concentrating
mechanisms; both abbreviated as CCMs) presumably evolved under conditions of low CO 2 …

Examination of Triacylglycerol Biosynthetic Pathways via De Novo Transcriptomic and Proteomic Analyses in an Unsequenced Microalga

MT Guarnieri, A Nag, SL Smolinski, A Darzins… - PloS one, 2011 - journals.plos.org
Biofuels derived from algal lipids represent an opportunity to dramatically impact the global
energy demand for transportation fuels. Systems biology analyses of oleaginous algae …

Linking toxicity and adaptive responses across the transcriptome, proteome, and phenotype of Chlamydomonas reinhardtii exposed to silver

S Pillai, R Behra, H Nestler, MJF Suter… - Proceedings of the …, 2014 - National Acad Sciences
Understanding mechanistic and cellular events underlying a toxicological outcome allows
the prediction of impact of environmental stressors to organisms living in different habitats. A …

[HTML][HTML] Green systems biology—from single genomes, proteomes and metabolomes to ecosystems research and biotechnology

W Weckwerth - Journal of proteomics, 2011 - Elsevier
Plants have shaped our human life form from the outset. With the emerging recognition of
world population feeding, global climate change and limited energy resources with fossil …

Application of targeted mass spectrometry in bottom-up proteomics for systems biology research

NP Manes, A Nita-Lazar - Journal of proteomics, 2018 - Elsevier
The enormous diversity of proteoforms produces tremendous complexity within cellular
proteomes, facilitates intricate networks of molecular interactions, and constitutes a …