Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP1)
exhibit incretin activity, meaning that they potentiate glucose-dependent insulin secretion …

The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐
like peptide‐1 (GLP‐1) have their main physiological role in augmenting insulin secretion …

The incretin system is an essential metabolic axis that regulates postprandial metabolism.
The two incretin peptides that enable this effect are the glucose-dependent insulinotropic …

Osteopontin (OPN) is a highly phosphorylated glycophosphoprotein having acidic
characteristics and rich in aspartic acid. OPN, a multifunctional protein, has important …

Oxidative stress and chronic inflammation are known to be associated with the development
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …

Incretin peptides, principally GLP-1 and GIP, regulate islet hormone secretion, glucose
concentrations, lipid metabolism, gut motility, appetite and body weight, and immune …

Since its first description more than 20 years ago osteopontin has emerged as an active
player in many physiological and pathological processes, including biomineralization, tissue …

Genetics, epigenetics, and environment may together affect the susceptibility for type 2
diabetes (T2D). Our aim was to dissect molecular mechanisms underlying T2D using …

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
are incretin hormones that control the secretion of insulin, glucagon, and somatostatin to …

Tirzepatide is a unimolecular co‐agonist of the glucagon‐like peptide‐1 (GLP‐1) and
glucose‐dependent insulinotropic polypeptide (GIP) receptors recently approved for the …