Background Locally advanced rectal cancer is routinely treated with neo-adjuvant long
course chemoradiotherapy or short course radiotherapy, followed by total mesorectal …

In colon cancer, primary surgery followed by postoperative chemotherapy represents the
standard of care. In rectal cancer, the standard of care is preoperative radiotherapy or …

Background/Aim: The combination of oxaliplatin, leucovorin and fluorouracil (FOLFOX) has
been established as postoperative adjuvant chemotherapy for stage III colon cancer …

Background Chemoradiation (CRT) or short-course radiotherapy (SCRT) are standard
treatments for locally advanced rectal cancer (LARC). We evaluated the efficacy/safety of …

Background There is continued debate regarding the optimal combinations of radiation
therapy and chemotherapy in the preoperative treatment of locally advanced rectal …

Background and purpose With the advent of more intensive chemotherapy regimens,
neoadjuvant chemoradiotherapy (NACRT) for patients with locally advanced rectal cancer …

Neo-adjuvant chemoradiation (NA-CRT) is the standard of management for the locally
advanced rectal cancer (LARC), achieving very low rates of local recurrence (LR). However …

Rectal cancer response to neoadjuvant Chemoradiotherapy (pCRT) is highly variable. In
fact, it has been estimated that only about 21% of patients show pathologic Complete …

OBJECTIVE. The objective of this study was to compare the prognoses of patients with low-
and high-risk rectal cancer detected by MRI who were treated without neoadjuvant …

Objective: The goal of this study was to investigate whether neoadjuvant chemoradiotherapy
(NCRT) plus total mesorectal excision (TME) would improve the outcome of patients with …