Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions

B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

The role of allergen‐specific IgE, IgG and IgA in allergic disease

MH Shamji, R Valenta, T Jardetzky, V Verhasselt… - Allergy, 2021 - Wiley Online Library
Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease
affecting more than 30% of the population. Exposure to even minute quantities of allergens …

EAACI molecular allergology user's guide 2.0

S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …

Update on food allergy

RL Peters, M Krawiec, JJ Koplin… - Pediatric Allergy and …, 2021 - Wiley Online Library
Food allergy is a major public health issue with growing prevalence in the urbanized world
and significant impact on the lives of allergic patients and their families. Research into the …

CD23+IgG1+ memory B cells are poised to switch to pathogenic IgE production in food allergy

M Ota, KB Hoehn, W Fernandes-Braga, T Ota… - Science translational …, 2024 - science.org
Food allergy is caused by allergen-specific immunoglobulin E (IgE) antibodies, but little is
known about the B cell memory of persistent IgE responses. Here, we describe, in human …

[HTML][HTML] Feast for thought: a comprehensive review of food allergy 2021-2023

I Bartha, N Almulhem, AF Santos - Journal of Allergy and Clinical …, 2024 - Elsevier
A review of the latest publications in food allergy over the past couple of years confirmed that
food allergy is a major public health concern, affecting about 8% of children and 10% of …

Therapeutic monoclonal antibodies in allergy: Targeting IgE, cytokine, and alarmin pathways

A Eggel, LF Pennington, TS Jardetzky - Immunological reviews, 2024 - Wiley Online Library
The etiology of allergy is closely linked to type 2 inflammatory responses ultimately leading
to the production of allergen‐specific immunoglobulin E (IgE), a key driver of many allergic …

Metabolism in type 2 immune responses

AM Kabat, EL Pearce, EJ Pearce - Immunity, 2023 - cell.com
The immune response is tailored to the environment in which it takes place. Immune cells
sense and adapt to changes in their surroundings, and it is now appreciated that in addition …

Exploring the molecular mechanisms underlying the protective effects of microbial SCFAs on intestinal tolerance and food allergy

M Luu, H Monning, A Visekruna - Frontiers in immunology, 2020 - frontiersin.org
A body of evidence suggests that food allergy (FA) has increased in prevalence over the
past few decades. Novel findings support the hypothesis that some commensal bacteria and …

Intestinal mucus barrier: a missing piece of the puzzle in food allergy

A Parrish, M Boudaud, A Kuehn, M Ollert… - Trends in Molecular …, 2022 - cell.com
The prevalence of food allergies has reached epidemic levels but the cause remains largely
unknown. We discuss the clinical relevance of the gut mucosal barrier as a site for allergic …