Current and future perspectives of liquid biopsies in genomics-driven oncology
Precision oncology seeks to leverage molecular information about cancer to improve patient
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …
Epigenetic alterations in colorectal cancer: emerging biomarkers
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …
fundamental processes driving the initiation and progression of CRC is the accumulation of …
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
Plasma consists of DNA released from multiple tissues within the body. Using genome-wide
bisulfite sequencing of plasma DNA and deconvolution of the sequencing data with …
bisulfite sequencing of plasma DNA and deconvolution of the sequencing data with …
Physical exercise as an epigenetic modulator of brain plasticity and cognition
J Fernandes, RM Arida, F Gomez-Pinilla - Neuroscience & Biobehavioral …, 2017 - Elsevier
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …
function, the effects of which can last for considerable time. An emerging line of scientific …
Point of care testing for infectious diseases
Infectious diseases are caused by pathogenic microorganisms and can be transmitted
between individuals and populations thus threatening the general public health and …
between individuals and populations thus threatening the general public health and …
[HTML][HTML] Extracellular/circulating microRNAs: release mechanisms, functions and challenges
MH Sohel - Achievements in the Life Sciences, 2016 - Elsevier
MicroRNAs (miRNAs) are endogenously initiated, small non-coding RNAs and typically
regulate the expression of mRNAs in post transcriptional level either via translational …
regulate the expression of mRNAs in post transcriptional level either via translational …
[HTML][HTML] Circulating biomarkers for early detection and clinical management of colorectal cancer
M Marcuello, V Vymetalkova, RPL Neves… - Molecular Aspects of …, 2019 - Elsevier
New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …
colorectal cancer (CRC) screening and management are urgently needed. A growing …
Clinical relevance of circulating cell-free microRNAs in cancer
H Schwarzenbach, N Nishida, GA Calin… - Nature reviews Clinical …, 2014 - nature.com
Efficient patient management relies on early diagnosis of disease and monitoring of
treatment. In this regard, much effort has been made to find informative, blood-based …
treatment. In this regard, much effort has been made to find informative, blood-based …
Stability of circulating blood-based microRNAs–pre-analytic methodological considerations
Background and aim The potential of microRNAs (miRNA) as non-invasive diagnostic,
prognostic, and predictive biomarkers, as well as therapeutic targets, has recently been …
prognostic, and predictive biomarkers, as well as therapeutic targets, has recently been …
MicroRNA profiling: approaches and considerations
CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …
thousands of genes in a broad range of organisms in both normal physiological contexts …