The potential of oxygenation-sensitive CMR in heart failure

E Hillier, MG Friedrich - Current Heart Failure Reports, 2021 - Springer
Abstract Purpose of Review Cardiac magnetic resonance imaging (CMR) use in the context
of heart failure (HF) has increased over the last decade as it is able to provide detailed …

Response of myocardial oxygenation to breathing manoeuvres and adenosine infusion

K Fischer, DP Guensch… - European Heart Journal …, 2015 - academic.oup.com
Aims Testing for inducible myocardial ischaemia is one of the most important diagnostic
procedures and has a strong impact on clinical decision-making. Current standard protocols …

[HTML][HTML] Breathing maneuvers as a vasoactive stimulus for detecting inducible myocardial ischemia–an experimental cardiovascular magnetic resonance study

K Fischer, DP Guensch, N Shie, J Lebel, MG Friedrich - PLoS One, 2016 - journals.plos.org
Background Breathing maneuvers can elicit a similar vascular response as vasodilatory
agents like adenosine; yet, their potential diagnostic utility in the presence of coronary artery …

Hyperoxia exacerbates myocardial ischemia in the presence of acute coronary artery stenosis in swine

DP Guensch, K Fischer, N Shie, J Lebel… - Circulation …, 2015 - Am Heart Assoc
Background—Current guidelines limit the use of high oxygen tension after return of
spontaneous circulation after cardiac arrest, focusing on neurological outcome and mortality …

[HTML][HTML] Impact of hyperventilation and apnea on myocardial oxygenation in patients with obstructive sleep apnea–An oxygenation-sensitive CMR study

F Roubille, K Fischer, DP Guensch, JC Tardif… - Journal of …, 2017 - Elsevier
Background Oxygenation-sensitive cardiovascular magnetic resonance imaging (OS-CMR)
is an emerging technique that can monitor changes in myocardial oxygenation in vivo …

Myocardial effective transverse relaxation time Correlates with left ventricular wall thickness: A 7.0 T MRI study

T Huelnhagen, F Hezel… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose Myocardial effective relaxation time is commonly regarded as a surrogate for
myocardial tissue oxygenation. However, it is legitimate to assume that there are multiple …

[HTML][HTML] Relationship between myocardial oxygenation and blood pressure: Experimental validation using oxygenation-sensitive cardiovascular magnetic resonance

DP Guensch, K Fischer, C Jung, S Hurni, BM Winkler… - PLoS …, 2019 - journals.plos.org
Background The relationship between mean arterial pressure (MAP) and coronary blood
flow is well described. There is autoregulation within a MAP range of 60 to 140 mmHg …

Breathing maneuvers as a coronary vasodilator for myocardial perfusion imaging

T Teixeira, G Nadeshalingam, K Fischer… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose A combined breathing maneuver of hyperventilation, followed by a long voluntary
breathhold leads to coronary vasodilation. We investigated the impact of breathing …

[HTML][HTML] Cardiac hypoxic resistance and decreasing lactate during maximum apnea in elite breath hold divers

T Kjeld, J Møller, K Fogh, EG Hansen, HC Arendrup… - Scientific reports, 2021 - nature.com
Breath-hold divers (BHD) enduring apnea for more than 4 min are characterized by
resistance to release of reactive oxygen species, reduced sensitivity to hypoxia, and low …

[HTML][HTML] Myocardial T2* Mapping with Ultrahigh Field Magnetic Resonance: Physics and Frontier Applications

T Huelnhagen, K Paul, MC Ku, T Serradas Duarte… - Frontiers in …, 2017 - frontiersin.org
Cardiovascular magnetic resonance imaging (CMR) has become an indispensable clinical
tool for the assessment of morphology, function and structure of the heart muscle. By …