Why was early therapeutic research on psychedelic drugs abandoned?

W Hall - Psychological Medicine, 2022 - cambridge.org
BackgroundAdvocates of the therapeutic use of psychedelic drugs have argued that a
promising approach to treatment was prematurely abandoned in the 1960s primarily …

A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders

S Kisely, M Connor, AA Somogyi… - Australian & New …, 2023 - journals.sagepub.com
Objectives: There is an increasing interest in combining psilocybin or
methylenedioxymethamphetamine with psychological support in treating psychiatric …

Pattern breaking: a complex systems approach to psychedelic medicine

I Hipólito, J Mago, FE Rosas… - Neuroscience of …, 2023 - academic.oup.com
Recent research has demonstrated the potential of psychedelic therapy for mental health
care. However, the psychological experience underlying its therapeutic effects remains …

The Global Psychedelic Survey: Consumer characteristics, patterns of use, and access in primarily anglophone regions around the world

S Lake, P Lucas - International Journal of Drug Policy, 2024 - Elsevier
Objectives Despite advancements in policies governing psychedelic substances globally,
our understanding of real-world psychedelic use and its variations across international …

Predicting the hallucinogenic potential of molecules using artificial intelligence

F Urbina, T Jones, JS Harris, SH Snyder… - ACS Chemical …, 2024 - ACS Publications
The development of new drugs addressing serious mental health and other disorders
should avoid the psychedelic experience. Analogs of psychedelic drugs can have clinical …

Changed substance use after psychedelic experiences among individuals in Canada

KF Boehnke, DJ Kruger, P Lucas - … Journal of Mental Health and Addiction, 2024 - Springer
We conducted a cross-sectional online survey of adults (n= 1639; 56.3% women) self-
reporting past or current psychedelic use. We investigated whether psychedelic use was …

Mini-review: the neurobiology of treating substance use disorders with classical psychedelics

MM Urban, MR Stingl, MW Meinhardt - Frontiers in Neuroscience, 2023 - frontiersin.org
The potential of psychedelics to persistently treat substance use disorders is known since
the 1960s. However, the biological mechanisms responsible for their therapeutic effects …

The frontiers of new psychedelic therapies: A survey of sociological themes and issues

T Andrews, K Wright - Sociology Compass, 2022 - Wiley Online Library
Psychedelic compounds are on the cusp of being approved by medical regulators for
treatment‐resistant mental health disorders. Following promising clinical trials, and as rates …

A critical appraisal of evidence on the efficacy and safety of serotonergic psychedelic drugs as emerging antidepressants: mind the evidence gap

N Ledwos, JD Rosenblat, DM Blumberger… - Journal of Clinical …, 2022 - journals.lww.com
MATERIALS AND METHODS We present a narrative review of the published literature
conducted by identifying contemporary clinical trials of serotonergic psychedelics for the …

Application of machine learning and complex network measures to an EEG dataset from ayahuasca experiments

CL Alves, RG Cury, K Roster, AM Pineda… - Plos one, 2022 - journals.plos.org
Ayahuasca is a blend of Amazonian plants that has been used for traditional medicine by
the inhabitants of this region for hundreds of years. Furthermore, this plant has been …