Stepping on the gas to a circular economy: accelerating development of carbon-negative chemical production from gas fermentation

N Fackler, BD Heijstra, BJ Rasor… - Annual review of …, 2021 - annualreviews.org
Owing to rising levels of greenhouse gases in our atmosphere and oceans, climate change
poses significant environmental, economic, and social challenges globally. Technologies …

[HTML][HTML] Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy

M Pavan, K Reinmets, S Garg, AP Mueller… - Metabolic …, 2022 - Elsevier
High levels of anthropogenic CO 2 emissions are driving the warming of global climate. If
this pattern of increasing emissions does not change, it will cause further climate change …

Embracing a low-carbon future by the production and marketing of C1 gas protein

J Xu, J Wang, C Ma, Z Wei, Y Zhai, N Tian, Z Zhu… - Biotechnology …, 2023 - Elsevier
Food scarcity and environmental deterioration are two major problems that human
populations currently face. Fortunately, the disruptive innovation of raw food materials has …

[HTML][HTML] CRISPR-based approaches for gene regulation in non-model bacteria

SN Call, LB Andrews - Frontiers in genome editing, 2022 - frontiersin.org
CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) have become
ubiquitous approaches to control gene expression in bacteria due to their simple design and …

[HTML][HTML] Substituting Fish Meal with a Bacteria Protein (Clostridium autoethanogenum Protein) Derived from Industrial-Scale Gas Fermentation: Effects on Growth and Gut Health …

J Zhang, Y Dong, K Song, L Wang, X Li, K Lu, B Tan… - Fishes, 2022 - mdpi.com
This study was conducted to investigate the effects of Clostridium autoethanogenum protein
(CAP) replacement for fish meal (FM) on growth performance, digestive enzyme activity …

Spacer2PAM: A computational framework to guide experimental determination of functional CRISPR-Cas system PAM sequences

GA Rybnicky, NA Fackler, AS Karim… - Nucleic acids …, 2022 - academic.oup.com
RNA-guided nucleases from CRISPR-Cas systems expand opportunities for precise,
targeted genome modification. Endogenous CRISPR-Cas systems in many prokaryotes are …

[HTML][HTML] Recent progress in engineering Clostridium autoethanogenum to synthesize the biochemicals and biocommodities

S Wan, M Lai, X Gao, M Zhou, S Yang, Q Li, F Li… - Synthetic and Systems …, 2023 - Elsevier
Excessive mining and utilization fossil fuels has led to drastic environmental consequences,
which will contribute to global warming and cause further climate change with severe …

[HTML][HTML] Integrating greenhouse gas capture and C1 biotechnology: a key challenge for circular economy

JL García, B Galán - Microbial Biotechnology, 2022 - ncbi.nlm.nih.gov
Integrating greenhouse gas capture and C1 biotechnology: a key challenge for circular economy
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

[HTML][HTML] Single and multiplexed gene repression in solventogenic Clostridium via Cas12a-based CRISPR interference

RC Joseph, NR Sandoval - Synthetic and Systems Biotechnology, 2023 - Elsevier
The Gram-positive, spore-forming, obligate anaerobic firmicute species that make up the
Clostridium genus have broad feedstock consumption capabilities and produce value …

[HTML][HTML] Agr Quorum Sensing influences the Wood-Ljungdahl pathway in Clostridium autoethanogenum

P Piatek, C Humphreys, MP Raut, PC Wright… - Scientific Reports, 2022 - nature.com
Acetogenic bacteria are capable of fermenting CO2 and carbon monoxide containing waste-
gases into a range of platform chemicals and fuels. Despite major advances in genetic …