MicroRNA-155 and antiviral immune responses

A Jafarzadeh, A Naseri, L Shojaie, M Nemati… - International …, 2021 - Elsevier
The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …

miRNA pathway alteration in response to non-coding RNA delivery in viral vector-based gene therapy

DA Savenkova, ALA Makarova, IK Shalik… - International Journal of …, 2022 - mdpi.com
Gene therapy is widely used to treat incurable disorders and has become a routine
procedure in clinical practice. Since viruses can exhibit specific tropisms, effectively …

MicroRNA-27a, downregulated in human obesity, exerts an antiapoptotic function in adipocytes

L Liu, D Li, C Peng, R Gao, X Li, L Zhang, Q Lv… - Endocrine …, 2023 - jstage.jst.go.jp
Adipocyte apoptosis is a key initial event that contributes to macrophage infiltration into
adipose tissue (AT) and thus triggers AT inflammation in obesity. MicroRNA-27a (miR-27a) …

Bta-miR-376a Targeting KLF15 Interferes with Adipogenesis Signaling Pathway to Promote Differentiation of Qinchuan Beef Cattle Preadipocytes

X Chen, SHA Raza, G Cheng, X Ma, J Wang, L Zan - Animals, 2020 - mdpi.com
Simple Summary Our study demonstrated that bta-miR-376a negatively regulates adipocyte
proliferation and differentiation by targeting the adipogenesis signaling pathway and is thus …

Adenovirus 36 seropositivity is related to the expression of anti-adipogenic lncRNAs GAS5 and MEG3 in adipose tissue obtained from subjects with obesity

V Manríquez, R Brito, M Pavez, J Sapunar… - International Journal of …, 2024 - nature.com
Abstract Background Human Adenovirus D-36 (HAdV-D36) promotes adipogenesis in
cellular and animal models and may contribute to the development of human obesity …

Presence of adenovirus-36 DNA in adipose tissue of women: Relationship with adipocyte morphology and the expression of C/EBPβ and HIF-1α

J Barrera-Alcocer, L García-Benavides… - Diabetes, Metabolic …, 2021 - Taylor & Francis
Background Human adenovirus 36 (HAd36) infection has been associated with obesity.
Experiments using 3T3-L1 adipocyte cultured cells and human adipose stem cells (hASCc) …

High serum miR-421 is associated with metabolic dysregulation and inflammation in patients with metabolic syndrome

AA Braga, RH Bortolin, ME Graciano-Saldarriaga… - …, 2021 - Taylor & Francis
Aim: To explore the association of circulating miRNAs with adiposity, metabolic status and
inflammatory biomarkers in patients with metabolic syndrome (MetS). Methods: Serum levels …

Adenovirus 36 infection and obesity risk: current understanding and future therapeutic strategies

ACL Cancelier, F Schuelter-Trevisol… - Expert Review of …, 2022 - Taylor & Francis
Introduction Obesity, a multifactorial disease caused by the interaction between genetic
characteristics, metabolism, lifestyle, and environmental factors, is a major global health …

Adenovirus 36 seropositivity influences the expression of anti-adipogenic lncRNAs GAS5 and MEG3 in adipose tissue obtained from subjects with obesity

A Cerda, V Manriquez, R Brito, M Pavez, J Sapunar… - 2023 - researchsquare.com
Background Adenovirus 36 (Ad-36) promotes adipogenesis and the development of human
obesity. Induction of PPARγ by Ad-36 seems to have a central role in maintenance of …

Metabolic Reprogramming By DNA Tumour Viruses

M Prusinkiewicz - 2021 - search.proquest.com
Viruses are the etiological agents of approximately 12% of human cancers. However, only a
subset of viral infections eventually progress to cancer. As obligate intracellular parasites …