Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Cosmetics preservation: a review on present strategies

N Halla, IP Fernandes, SA Heleno, P Costa… - Molecules, 2018 - mdpi.com
Cosmetics, like any product containing water and organic/inorganic compounds, require
preservation against microbial contamination to guarantee consumer's safety and to …

Role of bacterial motility in differential resistance mechanisms of silver nanoparticles and silver ions

LM Stabryla, KA Johnston, NA Diemler… - Nature …, 2021 - nature.com
Unlike conventional antimicrobials, the study of bacterial resistance to silver nanoparticles
(AgNPs) remains in its infancy and the mechanism (s) through which it evolves are limited …

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

CJ Chang, CS Lin, CC Lu, J Martel, YF Ko… - Nature …, 2015 - nature.com
Obesity is associated with low-grade chronic inflammation and intestinal dysbiosis.
Ganoderma lucidum is a medicinal mushroom used in traditional Chinese medicine with …

Biofilm-specific antibiotic tolerance and resistance

I Olsen - European Journal of Clinical Microbiology & Infectious …, 2015 - Springer
Biofilms are heterogeneous structures composed of bacterial cells surrounded by a matrix
and attached to solid surfaces. The bacteria here are 100 to 1,000 times more tolerant to …

Targeting metalloenzymes for therapeutic intervention

AY Chen, RN Adamek, BL Dick, CV Credille… - Chemical …, 2018 - ACS Publications
Metalloenzymes are central to a wide range of essential biological activities, including
nucleic acid modification, protein degradation, and many others. The role of metalloenzymes …

The multifaceted roles of antibiotics and antibiotic resistance in nature

S Sengupta, MK Chattopadhyay… - Frontiers in …, 2013 - frontiersin.org
Antibiotics are chemotherapeutic agents, which have been a very powerful tool in the clinical
management of bacterial diseases since the 1940s. However, benefits offered by these …

Pseudomonas aeruginosa: all roads lead to resistance

EBM Breidenstein, C de la Fuente-Núñez… - Trends in …, 2011 - cell.com
Pseudomonas aeruginosa is often resistant to multiple antibiotics and consequently has
joined the ranks of 'superbugs' due to its enormous capacity to engender resistance. It …

A field guide to bacterial swarming motility

DB Kearns - Nature reviews microbiology, 2010 - nature.com
How bacteria regulate, assemble and rotate flagella to swim in liquid media is reasonably
well understood. Much less is known about how some bacteria use flagella to move over the …

Biofilm-specific antibiotic resistance

TF Mah - Future microbiology, 2012 - Taylor & Francis
Bacterial biofilms are the basis of many persistent diseases. The persistence of these
infections is primarily attributed to the increased antibiotic resistance exhibited by the cells …