Metabolic syndrome (MetS) is a disease composed of different risk factors such as obesity,
type 2 diabetes or dyslipidemia. The prevalence of this syndrome is increasing worldwide in …

Non-alcoholic fatty liver disease (NAFLD) is recognized as the most common type of chronic
liver disease in Western countries. Insulin resistance is a key factor in the pathogenesis of …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …

Non-alcoholic fatty liver disease (NAFLD) is currently not a component of the diagnostic
criteria for metabolic syndrome (MetS); however, the development of NAFLD has some …

Spleen has been considered a neglected organ so far, even though is strictly linked to liver.
The spleen plays an important role in the modulation of the immune system and in the …

As an intracellular polypeptide, heat shock protein 70 (HSP70) can be exposed on the
plasma membrane and/or released into the circulation. However, the role of HSP70 in …

Background Simvastatin exerts pleiotropic effects on cardiovascular system. However, its
effect on non-alcoholic fatty liver disease, especially the liver fibrosis, remains obscure. We …

Oxidants are generated by all cells during normal oxidative respiration, and as long as they
are under the control of appropriate mechanisms, they act as intracellular signaling …

Excessive fat liver is an important manifestation of nonalcoholic fatty liver disease (NAFLD),
associated with obesity, insulin resistance, and oxidative stress. In the present study, the …

Chronic liver diseases (CLDs) such as hepatitis, alcoholic liver disease, nonalcoholic fatty
liver, and their downstream effect cancer affect more than a billion of people around the …