Scaffold attachment factor A (SAF-A) or hnRNP U is a nuclear RNA-binding protein with a
well-documented role in processing newly transcribed RNA. Recent studies also indicate …

Mouse models have made innumerable contributions to understanding the genetic basis of
neurological disease and pathogenic mechanisms and to therapy development. Here we …

Advances in genetic discoveries have created substantial opportunities for precision
medicine in neurodevelopmental disorders. Many of the genes implicated in these diseases …

ABSTRACT Genetic variants affecting Heterogeneous Nuclear Ribonucleoprotein U
(HNRNPU) have been identified in several neurodevelopmental disorders (NDDs) …

Generating effective therapies for neurodevelopmental disorders has remained elusive. An
emerging drug discovery approach for neurodevelopmental disorders is to characterize …

A rampant and urgent global health issue of the 21st century is the emergence and
progression of fatty liver disease (FLD), including alcoholic fatty liver disease and the more …

Synapses connect discrete neurons into vast networks that send, receive, and encode
diverse forms of information. Synaptic function and plasticity, the neuronal process of …

Postnatal cortical and hippocampal mouse primary neuronal cultures are powerful and
widely-used models of neuronal activity and neurological disease. While this model is …

Advances in genetic discoveries have created substantial opportunities for precision
medicine in neurodevelopmental disorders. Many of the genes implicated in these diseases …