[HTML][HTML] Sjögren's syndrome: a systemic autoimmune disease

S Negrini, G Emmi, M Greco, M Borro… - Clinical and …, 2022 - Springer
Sjögren's syndrome is a chronic autoimmune disease characterized by ocular and oral
dryness resulting from lacrimal and salivary gland dysfunction. Besides, a variety of systemic …

Sjögren syndrome

P Brito-Zerón, C Baldini, H Bootsma… - Nature reviews Disease …, 2016 - nature.com
Sjögren syndrome (SjS) is a systemic autoimmune disease that primarily affects the exocrine
glands (mainly the salivary and lacrimal glands) and results in the severe dryness of …

Current and future use of chloroquine and hydroxychloroquine in infectious, immune, neoplastic, and neurological diseases: a mini-review

D Plantone, T Koudriavtseva - Clinical drug investigation, 2018 - Springer
The process of finding new therapeutic indications for currently used drugs, defined as
'repurposing', is receiving growing attention. Chloroquine and hydroxychloroquine, with an …

[HTML][HTML] A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome

P Soret, C Le Dantec, E Desvaux, N Foulquier… - Nature …, 2021 - nature.com
There is currently no approved treatment for primary Sjögren's syndrome, a disease that
primarily affects adult women. The difficulty in developing effective therapies is-in part …

[HTML][HTML] Pathogenesis and treatment of Sjogren's syndrome: review and update

Q Zhan, J Zhang, Y Lin, W Chen, X Fan… - Frontiers in …, 2023 - frontiersin.org
Sjogren's syndrome (SS) is a chronic autoimmune disease accompanied by multiple
lesions. The main manifestations include dryness of the mouth and eyes, along with …

Characterization of systemic disease in primary Sjögren's syndrome: EULAR-SS Task Force recommendations for articular, cutaneous, pulmonary and renal …

M Ramos-Casals, P Brito-Zerón, R Seror… - …, 2015 - academic.oup.com
Abstract Objective. To reach a European consensus on the definition and characterization of
the main organ-specific extraglandular manifestations in primary SS. Methods. The EULAR …

How immunological profile drives clinical phenotype of primary Sjogren's syndrome at diagnosis: analysis of 10,500 patients (Sjogren Big Data Project)

P Brito-Zerón, N Acar-Denizli, WF Ng… - Clinical and …, 2018 - research.rug.nl
Objective. To evaluate the influence of the main immunological markers on the disease
phenotype at diagnosis in a large international cohort of patients with primary Sjogren's …

[HTML][HTML] Reviewing primary Sjögren's syndrome: beyond the dryness-From pathophysiology to diagnosis and treatment

T Both, VASH Dalm, PM van Hagen… - International journal of …, 2017 - ncbi.nlm.nih.gov
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease, characterized by
lymphocytic infiltration of the secretory glands. This process leads to sicca syndrome, which …

Renal involvement in primary Sjögren syndrome

H François, X Mariette - Nature Reviews Nephrology, 2016 - nature.com
Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by
lymphoplasmacytic infiltration of the exocrine (salivary and lachrymal) glands that results in …

Google-driven search for big data in autoimmune geoepidemiology: analysis of 394,827 patients with systemic autoimmune diseases

M Ramos-Casals, P Brito-Zerón, B Kostov… - Autoimmunity …, 2015 - Elsevier
Systemic autoimmune diseases (SADs) are a significant cause of morbidity and mortality
worldwide, although their epidemiological profile varies significantly country by country. We …