[HTML][HTML] The effect of inflammation and infection on lipids and lipoproteins

KR Feingold, C Grunfeld - Endotext [internet], 2022 - ncbi.nlm.nih.gov
Chronic inflammatory diseases, such as rheumatoid arthritis (RA), systemic lupus
erythematosus (SLE), and psoriasis and infections, such as periodontal disease and HIV …

The many roles of cholesterol in sepsis: a review

DA Hofmaenner, A Kleyman, A Press… - American journal of …, 2022 - atsjournals.org
The biological functions of cholesterol are diverse, ranging from cell membrane integrity, cell
membrane signaling, and immunity to the synthesis of steroid and sex hormones, vitamin D …

U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies

CM Madsen, A Varbo, A Tybjærg-Hansen… - European heart …, 2018 - academic.oup.com
Aims Preclinical evidence has indicated that HDL may play an important role in the immune
system; however, very little is known about the role of HDL in the immune system in humans …

Inhibition of cholesteryl ester transfer protein preserves high-density lipoprotein cholesterol and improves survival in sepsis

M Trinder, Y Wang, CM Madsen, T Ponomarev… - Circulation, 2021 - Am Heart Assoc
Background: The high-density lipoprotein hypothesis of atherosclerosis has been
challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors, which …

Similar but not the same: differential diagnosis of HLH and sepsis

R Machowicz, G Janka, W Wiktor-Jedrzejczak - Critical reviews in oncology …, 2017 - Elsevier
Differential diagnosis of hemophagocytic lymphohistiocytosis (HLH; hemophagocytic
syndrome) and sepsis is critically important because the life-saving aggressive …

[HTML][HTML] Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study

G Wang, Q Zhang, X Zhao, H Dong, C Wu, F Wu… - Lipids in health and …, 2020 - Springer
Background The purpose of the study is to describe the blood lipid levels of patients
diagnosed with coronavirus disease 2019 (COVID-19) and to analyze the correlation …

[HTML][HTML] Low circulatory levels of total cholesterol, HDL-C and LDL-C are associated with death of patients with sepsis and critical illness: systematic review, meta …

R Taylor, C Zhang, D George, S Kotecha… - …, 2024 - thelancet.com
Background Mechanistic studies have established a biological role of sterol metabolism in
infection and immunity with clinical data linking deranged cholesterol metabolism during …

Effect of inflammation on HDL structure and function

KR Feingold, C Grunfeld - Current opinion in lipidology, 2016 - journals.lww.com
During inflammation multiple changes in HDL structure occur leading to alterations in HDL
function. In the short term, these changes may be beneficial resulting in an increase in …

Causal inference for genetically determined levels of high-density lipoprotein cholesterol and risk of infectious disease

M Trinder, KR Walley, JH Boyd… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: HDL (high-density lipoprotein) cholesterol (HDL-C) and LDL (low-density
lipoprotein) cholesterol (LDL-C) are inversely associated with infectious hospitalizations …

Decreased high-density lipoprotein cholesterol level is an early prognostic marker for organ dysfunction and death in patients with suspected sepsis

M Cirstea, KR Walley, JA Russell, LR Brunham… - Journal of critical …, 2017 - Elsevier
Purpose We sought to determine whether an early high-density lipoprotein cholesterol (HDL-
C) measurement at emergency department (ED) admission is prognostic of multiorgan …