SLC7A11/xCT is an antiporter that mediates the uptake of extracellular cystine in exchange
for glutamate. Cystine is reduced to cysteine, which is a rate-limiting precursor in glutathione …

The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …

Obesity is closely related to a poor prognosis in patients with advanced colorectal cancer
(CRC), but the mechanisms remain unclear. Ferroptosis is a form of nonapoptotic cell death …

Mesenchymal stem cells (MSCs) have attracted interest for their potential to alleviate liver
injury. Here, the protective effect of MSCs on carbon tetrachloride (CCl4)-induced acute liver …

Background Colorectal carcinoma (CRC) is one of the most common malignant tumors, and
its main cause of death is tumor metastasis. RNA N 6-methyladenosine (m 6 A) is an …

Ferroptosis is a type of oxidative stress-dependent regulated necrosis characterized by
excessive lipid peroxide accumulation. This novel cell death modality has been implicated in …

Anoikis is a critical obstacle to cancer metastasis. Colorectal cancer (CRC) exhibits a high
rate of metastasis, leading to death, and the mechanisms involved in anoikis resistance are …

Background Gastric cancer stem cells (CSCs) are the main causes of metastasis and drug
resistance. We previously indicated that miR-375 can inhibit Helicobacter pylori-induced …

Cancer stem cells (CSCs), enabled to self-renew, differentiate, and initiate the bulk tumor,
are recognized as the culprit of treatment resistance, metastasis, and recurrence …

Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). However, the role of lncRNA in CRC liver metastasis remains …