Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Parkinson's disease (PD) is usually characterized by cardinal motor impairments. However,
a range of non-motor symptoms precede the motor-phase and are major determinants for …

Abstract Introduction The LipiDiDiet trial investigates the effects of the specific multinutrient
combination Fortasyn Connect on cognition and related measures in prodromal Alzheimer's …

Background Nutrition is an important modifiable risk factor in Alzheimer's disease. Previous
trials of the multinutrient Fortasyn Connect showed benefits in mild Alzheimer's disease …

Abstract Docosahexaenoic acid (DHA, C22: 6, ω-3) is a highly polyunsaturated omega-3
fatty acid. It is concentrated in neuronal brain membranes, for which reason it is also referred …

Impairment of amyloid‐β (Aβ) clearance leads to Aβ accumulation in the brain during the
development of Alzheimer's disease (AD). Strategies that can restore or improve the …

In the last decade, it has become obvious that Alzheimer's disease (AD) is closely linked to
changes in lipids or lipid metabolism. One of the main pathological hallmarks of AD is …

Subclinical vitamin C deficiency is widespread in many populations, but its role in both
Alzheimer's disease and normal aging is understudied. In the present study, we decreased …

Synapse loss and synaptic dysfunction are pathological processes already involved in the
early stages of Alzheimer's disease (AD). Synapses consist principally of neuronal …

The performance of the human brain is based on an interplay between the inherited
genotype and external environmental factors, including diet. Food and nutrition, essential in …