Evidence has revealed that transcription factors play essential roles in regulation of multiple
cellular processes, including cell proliferation, metastasis, EMT, cancer stem cells and …

The placenta is crucial for a successful pregnancy and the health of both the fetus and the
pregnant woman. However, how the human trophoblast lineage is regulated, including the …

The aim of this study is to review the methods being used for image analysis of microscopic
views of immunohistochemically stained specimen in medical research. The solutions …

Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

Background Although long-term estrogen (E2) exposure is associated with increased breast
cancer (BC) risk, and E2 appears to sustain growth of BC cells that express functional …

Proper differentiation of trophoblast cells in the human placenta is a prerequisite for a
successful pregnancy, and dysregulation of this process may lead to malignant pregnancy …

JARID1B is a member of the family of JmjC domain-containing proteins that removes methyl
residues from methylated lysine 4 on histone H3 lysine 4 (H3K4). JARID1B has been …

Abstract Background Cullin-7 (CUL7) is a member of the DOC domain-containing cullin
family and is involved in the regulation of cell transformation. However, the clinical …

Placenta accreta spectrum disorders (PAS) are severe pregnancy complications that occur
when extravillous trophoblast cells (EVTs) invade beyond the uterine inner myometrium and …

As the best adapted high altitude population, Tibetans feature a relatively high offspring
survival rate. Genome-wide studies have identified hundreds of candidate SNPs related to …