DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas

X Zhu, A Perales-Puchalt, K Wojtak, Z Xu, K Yun… - Molecular Therapy …, 2022 - cell.com
Latent Epstein-Barr virus (EBV) infection is associated with several types of cancer. Several
clinical studies have targeted EBV antigens as immune therapeutic targets with limited …

Adenoviral Transfer of Human Aquaporin-8 Gene to Mouse Liver Improves Ammonia-Derived Ureagenesis

AM Capiglioni, MC Capitani, J Marrone, RA Marinelli - Cells, 2023 - mdpi.com
We previously reported that, in cultured hepatocytes, mitochondrial aquaporin-8 (AQP8)
channels facilitate the conversion of ammonia to urea and that the expression of human …

Implications of sex and extra-hepatic ammonia metabolism in chronic liver disease and development of hepatic encephalopathy

M Macedo de Oliveira - 2022 - papyrus.bib.umontreal.ca
Background and aims: Hepatic encephalopathy (HE) is a neuropsychiatric disorder and a
major complication of chronic liver disease (CLD). HE manifests with a wide range of …