Respiratory syncytial virus infection and novel interventions

AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …

Open questions in the social lives of viruses

A Leeks, LM Bono, EA Ampolini… - Journal of …, 2023 - academic.oup.com
Social interactions among viruses occur whenever multiple viral genomes infect the same
cells, hosts, or populations of hosts. Viral social interactions range from cooperation to …

High accuracy of clinical verification of electrohydrodynamic-driven nanobox-on-mirror platform for molecular identification of respiratory viruses

J Li, R Guan, A Wuethrich, M Yan, J Cheng… - Analytical …, 2024 - ACS Publications
The molecular detection of multiple respiratory viruses provides evidence for the rational use
of drugs and effective health management. Herein, we developed and tested the clinical …

Targeted metagenomics reveals association between severity and pathogen co-detection in infants with respiratory syncytial virus

GL Lin, SB Drysdale, MD Snape, D O'connor… - Nature …, 2024 - nature.com
Respiratory syncytial virus (RSV) is the leading cause of hospitalisation for respiratory
infection in young children. RSV disease severity is known to be age-dependent and highest …

[HTML][HTML] Phylogenetic and pathogenic characterization of lumpy skin disease virus circulating in China

S Ren, H Chen, L Yuan, X Yang, TB Afera, ZU Rehman… - Virology, 2023 - Elsevier
The genomic characterization of emerging pathogens is critical for unraveling their origin
and tracking their dissemination. Lumpy skin disease virus (LSDV) is a rapidly emerging …

Quantification of multiple respiratory viruses in wastewater in the Kathmandu Valley, Nepal: Potential implications of wastewater-based epidemiology for community …

S Raya, B Malla, S Shrestha, N Sthapit, H Kattel… - Science of The Total …, 2024 - Elsevier
Despite being the major cause of death, clinical surveillance of respiratory viruses at the
community level is very passive, especially in developing countries. This study focused on …

The interactions of SARS-CoV-2 with cocirculating pathogens: Epidemiological implications and current knowledge gaps

A Wong, LA Barrero Guevara, E Goult, M Briga… - PLoS …, 2023 - journals.plos.org
Despite the availability of effective vaccines, the persistence of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) suggests that cocirculation with other pathogens …

Chiral Intranasal Nanovaccines as Antivirals for Respiratory Syncytial Virus

B Shi, A Qu, Z Li, Y Xiong, J Ji, L Xu, C Xu… - Advanced …, 2024 - Wiley Online Library
This study aimed to develop an intranasal nanovaccine by combining chiral nanoparticles
with the RSV pre‐fusion protein (RSV protein) to create L‐nanovaccine (L‐Vac). The results …

Human bocavirus 1 coinfection is associated with decreased cytokine expression in the rhinovirus‐induced first wheezing episode in children

P Hurme, R Sahla, B Rückert… - Clinical and …, 2023 - Wiley Online Library
Background Rhinovirus (RV)‐induced first wheezing episodes in children are associated
with a markedly increased risk of asthma. Previous studies have suggested that human …

[HTML][HTML] Aggravated exposure risks of children to multipath transmitted pathogens in indoor environments

Z Liu, L Hu, C Hu, Q Liu, Z Liang, R Rong, H Liu - Iscience, 2023 - cell.com
Considering the significance of multipath transmissions of respiratory pathogens in the post-
epidemic era, surprisingly little is acknowledged regarding the susceptibility, short-term …