[HTML][HTML] Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

A Ponte-Sucre, F Gamarro, JC Dujardin… - PLoS neglected …, 2017 - journals.plos.org
Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently
needed on a global basis because treatment failure is an increasing problem. Drug …

Vaccines to prevent leishmaniasis

R Kumar, C Engwerda - Clinical & translational immunology, 2014 - Wiley Online Library
Leishmaniasis is a parasitic disease that encompasses a range of clinical manifestations
affecting people in tropical and subtropical regions of the world. Epidemiological and …

Mechanism of amphotericin B resistance in clinical isolates of Leishmania donovani

B Purkait, A Kumar, N Nandi, AH Sardar… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The clinical value of amphotericin B, the mainstay therapy for visceral leishmaniasis in
sodium antimony gluconate-nonresponsive zones of Bihar, India, is now threatened by the …

[HTML][HTML] Immunobiology of visceral leishmaniasis

R Kumar, S Nylén - Frontiers in immunology, 2012 - frontiersin.org
Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania
donovani and Leishmania infantum (Leishmania chagasi in the Americas). These …

[HTML][HTML] Molecular diagnosis of visceral leishmaniasis

S Sundar, OP Singh - Molecular diagnosis & therapy, 2018 - Springer
Visceral leishmaniasis (VL), a deadly parasitic disease, is a major public health concern
globally. Countries affected by VL have signed the London Declaration on Neglected …

Chemotherapy of leishmaniasis: past, present and future

J Mishra, A Saxena, S Singh - Current medicinal chemistry, 2007 - ingentaconnect.com
Leishmaniasis is a parasitic disease caused by hemoflagellate, Leishmania spp. The
parasite is transmitted by the bite of an infected female phlebotomine sandfly. The disease is …

[HTML][HTML] Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

I Gow, NC Smith, D Stark, J Ellis - Parasites & Vectors, 2022 - Springer
Leishmania infections span a range of clinical syndromes and impact humans from many
geographic foci, but primarily the world's poorest regions. Transmitted by the bite of a female …

The status of combination therapy for visceral leishmaniasis: An updated review

J van Griensven, TPC Dorlo, E Diro… - The Lancet Infectious …, 2024 - thelancet.com
For the past 15 years, trials of combination therapy options for visceral leishmaniasis have
been conducted with the aim of identifying effective, and safe treatment regimens that were …

[HTML][HTML] Nanotechnology based solutions for anti-leishmanial impediments: a detailed insight

H Jamshaid, FU Din, GM Khan - Journal of Nanobiotechnology, 2021 - Springer
As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …

[HTML][HTML] Tackling drug resistance and other causes of treatment failure in leishmaniasis

GJ Wijnant, F Dumetz, L Dirkx, D Bulté… - Frontiers in Tropical …, 2022 - frontiersin.org
Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite.
The disease is transmitted by female sand flies and, depending on the infecting parasite …