Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Next generation sequencing of SARS-CoV-2 genomes: challenges, applications and opportunities

M Chiara, AM D'Erchia, C Gissi… - Briefings in …, 2021 - academic.oup.com
Various next generation sequencing (NGS) based strategies have been successfully used in
the recent past for tracing origins and understanding the evolution of infectious agents …

Detection of a SARS-CoV-2 variant of concern in South Africa

H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh… - Nature, 2021 - nature.com
Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating
conditions for substantial evolutionary changes to the virus,. Here we describe a newly …

Escape of SARS-CoV-2 501Y. V2 from neutralization by convalescent plasma

S Cele, I Gazy, L Jackson, SH Hwa, H Tegally, G Lustig… - Nature, 2021 - nature.com
SARS-CoV-2 variants of concern (VOC) have arisen independently at multiple locations,
and may reduce the efficacy of current vaccines that target the spike glycoprotein of SARS …

Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa

H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh… - medrxiv, 2020 - medrxiv.org
Continued uncontrolled transmission of the severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for …

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

H Tegally, JE San, M Cotten, M Moir, B Tegomoh… - Science, 2022 - science.org
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing
in Africa over the past year has led to a major increase in the number of sequences that …

[HTML][HTML] COVID-19 outbreak associated with a SARS-CoV-2 R. 1 lineage variant in a skilled nursing facility after vaccination program—Kentucky, March 2021

AM Cavanaugh - MMWR. Morbidity and Mortality Weekly Report, 2021 - cdc.gov
In a COVID-19 outbreak at a Kentucky SNF involving a newly introduced variant to the
region, unvaccinated residents and health care personnel (HCP) had 3.0 and 4.1 times the …

Persistent SARS-CoV-2 infection and intra-host evolution in association with advanced HIV infection

F Karim, MYS Moosa, BI Gosnell, S Cele, J Giandhari… - MedRxiv, 2021 - medrxiv.org
While most people effectively clear SARS-CoV-2, there are several reports of prolonged
infection in immunosuppressed individuals. Here we present a case of prolonged infection …

COVID-19: impact on the HIV and tuberculosis response, service delivery, and research in South Africa

Q Abdool Karim, C Baxter - Current HIV/AIDS Reports, 2022 - Springer
Abstract Purpose of Review To describe how mitigation measures against COVID-19 have
impacted HIV and TB research in South Africa. Recent Findings South Africa has the highest …

Rapid replacement of the Beta variant by the Delta variant in South Africa

H Tegally, E Wilkinson, CL Althaus, M Giovanetti… - MedRxiv, 2021 - medrxiv.org
The Beta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
emerged in South Africa in late 2020 and rapidly became the dominant variant, causing over …