This review article is concerned with the mathematical modelling of the mechanical
properties of the soft biological tissues that constitute the walls of arteries. Many important …

The mitral valve is a complex anatomical structure whose physiological functioning relies on
the biomechanical properties and structural integrity of its components. Their compromise …

The leaflets of the mitral valve interact with the mitral jet and significantly impact diastolic
flow patterns, but the effect of mitral valve morphology and kinematics on diastolic flow and …

The objective of this study was to develop a patient-specific finite element (FE) model of a
human mitral valve. The geometry of the mitral valve was reconstructed from multi-slice …

Treatment of mitral valve (MV) diseases requires comprehensive clinical evaluation and
therapy personalization to optimize outcomes. Finite-element models (FEMs) of MV …

We aim at testing the possibility to build patient-specific structural finite element models
(FEMs) of the mitral valve (MV) from cardiac magnetic resonance (CMR) imaging and to use …

Chitosan is being widely studied for tissue engineering applications due to its
biocompatibility and biodegradability. However, its use in load-bearing applications is …

In the past two decades, major advances have been made in the clinical evaluation and
treatment of valvular heart disease owing to the advent of noninvasive cardiac imaging …

Degenerative mitral valve disease is the main cause of primary mitral regurgitation with two
phenotypes: fibroelastic deficiency (FED) often with localized myxomatous degeneration …

Estimation of regional tissue stresses in the functioning heart valve remains an important
goal in our understanding of normal valve function and in developing novel engineered …