BACKGROUND Fertility loss during female ageing is associated with increasing basal FSH
and decreasing anti-Müllerian hormone (AMH) concentrations, together with compromised …

Abstract Sphingosine-1-phoshate (S1P) is a membrane sphingolipid involved in several
physiological processes, including cell proliferation, tissue growth, cell survival and …

Classically, follicle-stimulating hormone receptor (FSHR)-driven cAMP-mediated signaling
boosts human ovarian follicle growth and oocyte maturation. However, contradicting in vitro …

Vascular endothelial growth factor (VEGF) is crucial for follicle development through the
regulation of granulosa cell (GC) function in some mammals, but its mechanism is unclear in …

Abstract Oxygen concentration (0 2) in antral ovarian follicles is below that found in most
tissues, which is important for adequate granulosa cell function. The VEGF system is linked …

Previous research demonstrated that acute treatment with GnRH-antagonist, Acyline,
allowed follicle growth until⁓ 8.5 mm and no dominant follicle was selected. This study …

Purpose To assess the effects of the oocyte on mRNA abundance of FSHR, AMH and major
genes of the maturation cascade (AREG, EREG, ADAM17, EGFR, PTGS2, TNFAIP6, PTX3 …

Vitrification is a promising method for ovarian cortex preservation, however, oxidative stress
resulting from excessive free radical production can cause irreversible damage to the ovary …

Prolificacy is the ability to reproduce abundantly. Litter size, which is highly dependent on
ovulation rate, has a high economic value and it is a fundamental reproductive trait …

Increasing the efficiency of farm animal reproduction is necessary to reduce the
environmental impact of food production systems. One approach is to increase the number …