Translating 3D printed pharmaceuticals: From hype to real-world clinical applications

I Seoane-Viaño, SJ Trenfield, AW Basit… - Advanced Drug Delivery …, 2021 - Elsevier
Abstract Three-dimensional (3D) printing is a revolutionary technology that is disrupting
pharmaceutical development by enabling the production of personalised printlets (3D …

Challenges of fused deposition modeling 3D printing in pharmaceutical applications: where are we now?

C Parulski, O Jennotte, A Lechanteur… - Advanced drug delivery …, 2021 - Elsevier
In recent years, fused deposition modeling has become one of the most used three-
dimensional printing technologies in the pharmaceutical field. The production of …

Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance

S Bandari, D Nyavanandi, N Dumpa… - Advanced drug delivery …, 2021 - Elsevier
Interest in 3D printing for pharmaceutical applications has increased in recent years.
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …

Additive manufacturing of antibacterial PLA-ZnO nanocomposites: Benefits, limitations and open challenges

WJ Chong, S Shen, Y Li, A Trinchi, D Pejak… - Journal of Materials …, 2022 - Elsevier
Polymeric biomaterials such as polylactic acid (PLA) play a prominent role in the
advancement of biomedical additive manufacturing (AM). PLA offers indeed a very …

Quality of FDM 3D printed medicines for pediatrics: considerations for formulation development, filament extrusion, printing process and printer design

J Quodbach, M Bogdahn, J Breitkreutz… - … Innovation & Regulatory …, 2021 - Springer
Abstract 3d printing is capable of providing dose individualization for pediatric medicines
and translating the precision medicine approach into practical application. In pediatrics …

Materials requirements in fused filament fabrication: a framework for the design of next‐generation 3D printable thermoplastics and composites

A Sola - Macromolecular Materials and Engineering, 2022 - Wiley Online Library
Fused filament fabrication (FFF), also known as fused deposition modeling, is the leading
technology for polymer‐based additive manufacturing. The simplicity, along with the …

Predicting drug release from 3D printed oral medicines based on the surface area to volume ratio of tablet geometry

H Windolf, R Chamberlain, J Quodbach - Pharmaceutics, 2021 - mdpi.com
3D printing offers the advantage of being able to modify dosage form geometry, which can
be exploited to modify release characteristics. In this study, we investigated the influence of …

[HTML][HTML] 3D printing of LEGO® like designs with tailored release profiles for treatment of sleep disorder

AG Tabriz, MS Mithu, MD Antonijevic, L Vilain… - International journal of …, 2023 - Elsevier
Abstract 3D printed LEGO®-like designs are an attractive approach for the development of
compartmental delivery systems due to their potential for dose personalisation through the …

[HTML][HTML] 3D printed, personalized sustained release cortisol for patients with adrenal insufficiency

S Ayyoubi, EEM van Kampen, LI Kocabas… - International Journal of …, 2023 - Elsevier
The standard of care for patients with Adrenal Insufficiency (AI) is suboptimal. Administration
of hydrocortisone three times a day produces plasma cortisol fluctuations associated with …

[HTML][HTML] 3D printing of amorphous solid dispersions: A comparison of fused deposition modeling and drop-on-powder printing

N Gottschalk, M Bogdahn, J Quodbach - International Journal of …, 2023 - Elsevier
Nowadays, a high number of pipeline drugs are poorly soluble and require solubility
enhancement by eg, manufacturing of amorphous solid dispersion. Pharmaceutical 3D …