Radiotherapy toxicity

D De Ruysscher, G Niedermann, NG Burnet… - Nature Reviews …, 2019 - nature.com
Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

Radiotherapy-induced digestive injury: diagnosis, treatment and mechanisms

G Chen, Y Han, H Zhang, W Tu, S Zhang - Frontiers in oncology, 2021 - frontiersin.org
Radiotherapy is one of the main therapeutic methods for treating cancer. The digestive
system consists of the gastrointestinal tract and the accessory organs of digestion (the …

Finite element-based personalized simulation of duodenal hydrogel spacer: Spacer location dependent duodenal sparing and a decision support system for spacer …

H Hooshangnejad, S Youssefian, A Narang… - Frontiers in …, 2022 - frontiersin.org
Purpose Pancreatic cancer is the fourth leading cause of cancer-related death, with a very
low 5-year overall survival rate (OS). Radiation therapy (RT) together with dose escalation …

Rectum-spacer related acute toxicity–endoscopy results of 403 prostate cancer patients after implantation of gel or balloon spacers

A Schörghofer, M Drerup, T Kunit, L Lusuardi… - Radiation …, 2019 - Springer
Background Rectal spacers are used to limit dose to the anterior rectal wall in high dose
external beam radiation therapy of the prostate and have been shown to reduce radiation …

[HTML][HTML] Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity

NR Franco, MC Massi, F Ieva, A Manzoni… - Radiotherapy and …, 2021 - Elsevier
Aim To identify the effect of single nucleotide polymorphism (SNP) interactions on the risk of
toxicity following radiotherapy (RT) for prostate cancer (PCa) and propose a new method for …

FEMOSSA: Patient‐specific finite element simulation of the prostate–rectum spacer placement, a predictive model for prostate cancer radiotherapy

H Hooshangnejad, S Youssefian, JK Guest… - Medical …, 2021 - Wiley Online Library
Purpose Major advances in delivery systems in recent years have turned radiotherapy (RT)
into a more effective way to manage prostate cancer. Still, adjacency of organs at risk …

Decision support systems in prostate cancer treatment: an overview

Y van Wijk, I Halilaj, E van Limbergen… - BioMed Research …, 2019 - Wiley Online Library
Background. A multifactorial decision support system (mDSS) is a tool designed to improve
the clinical decision‐making process, while using clinical inputs for an individual patient to …

[HTML][HTML] Ano-rectal wall dose-surface maps localize the dosimetric benefit of hydrogel rectum spacers in prostate cancer radiotherapy

BGL Vanneste, F Buettner, M Pinkawa… - Clinical and translational …, 2019 - Elsevier
Background and purpose To evaluate spatial differences in dose distributions of the ano-
rectal wall (ARW) using dose-surface maps (DSMs) between prostate cancer patients …

[HTML][HTML] Cost effectiveness of prostate cancer radiotherapy

A Konski - Translational Andrology and Urology, 2018 - ncbi.nlm.nih.gov
The use of radiotherapy in the treatment of prostate cancer has evolved from treatments
utilizing large fields with hand placed blocks to radiotherapy treatments given with a linear …

Hyperspectral imaging assessment for radiotherapy induced skin-erythema: pilot study

R Abdlaty, L Doerwald-Munoz, TJ Farrell… - Photodiagnosis and …, 2021 - Elsevier
Skin cancer (SC) is a widely spread disease in the USA, Canada, and Australia. Skin cancer
patients may be treated by many different techniques including radiation therapy. However …