Importance Among adults with chronic illness, 30% to 50% of medications are not taken as
prescribed. In the United States, it is estimated that medication nonadherence is associated …

Cardiovascular disease is the leading cause of death globally. While pharmacological
advancements have improved the morbidity and mortality associated with cardiovascular …

Background A polypill that includes key medications associated with improved outcomes
(aspirin, angiotensin-converting–enzyme [ACE] inhibitor, and statin) has been proposed as …

A key factor to successful secondary prevention of cardiovascular disease (CVD) is optimal
patient adherence to treatment. However, unsatisfactory rates of adherence to treatment for …

Background: Adherence to evidence-based cardiovascular (CV) medications after an acute
myocardial infarction (MI) is low after the first 6 months. The use of fixed-dose combinations …

Cardiovascular disease (CVD) is the second leading cause of mortality worldwide,
accounting for 17 million deaths in 2013. More than 80% of these cases were in low-and …

Background Persons with low socioeconomic status and nonwhite persons in the United
States have high rates of cardiovascular disease. The use of combination pills (also called …

Objectives To explore the effectiveness of data sharing by randomized controlled trials
(RCTs) in journals with a full data sharing policy and to describe potential difficulties …

Background Older people taking multiple medications represent a large and growing
proportion of the population. Managing multiple medications can be challenging, and this is …

Blood pressure control remains unsatisfactory in all countries of the world with at best 60%
of treated hypertensive patients reaching recommended therapeutic goals. Several factors …