Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Spatial and temporal scales of dopamine transmission

C Liu, P Goel, PS Kaeser - Nature Reviews Neuroscience, 2021 - nature.com
Dopamine is a prototypical neuromodulator that controls circuit function through G protein-
coupled receptor signalling. Neuromodulators are volume transmitters, with release followed …

The connectome of an insect brain

M Winding, BD Pedigo, CL Barnes, HG Patsolic, Y Park… - Science, 2023 - science.org
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

Electrically-transduced chemical sensors based on two-dimensional nanomaterials

Z Meng, RM Stolz, L Mendecki, KA Mirica - Chemical reviews, 2019 - ACS Publications
Electrically–transduced sensors, with their simplicity and compatibility with standard
electronic technologies, produce signals that can be efficiently acquired, processed, stored …

[PDF][PDF] A genetically encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice

F Sun, J Zeng, M Jing, J Zhou, J Feng, SF Owen, Y Luo… - Cell, 2018 - cell.com
Dopamine (DA) is a central monoamine neurotransmitter involved in many physiological
and pathological processes. A longstanding yet largely unmet goal is to measure DA …

Dopamine: functions, signaling, and association with neurological diseases

MO Klein, DS Battagello, AR Cardoso… - Cellular and molecular …, 2019 - Springer
The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …

[PDF][PDF] Structural insights into the human D1 and D2 dopamine receptor signaling complexes

Y Zhuang, P Xu, C Mao, L Wang, B Krumm, XE Zhou… - Cell, 2021 - cell.com
Summary The D1-and D2-dopamine receptors (D1R and D2R), which signal through G s
and G i, respectively, represent the principal stimulatory and inhibitory dopamine receptors …

[HTML][HTML] Dopamine receptor subtypes, physiology and pharmacology: new ligands and concepts in schizophrenia

JC Martel, S Gatti McArthur - Frontiers in pharmacology, 2020 - frontiersin.org
Dopamine receptors are widely distributed within the brain where they play critical
modulator roles on motor functions, motivation and drive, as well as cognition. The …

[HTML][HTML] Dopamine: The neuromodulator of long-term synaptic plasticity, reward and movement control

L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …

[PDF][PDF] The meningeal lymphatic system: a new player in neurophysiology

S Da Mesquita, Z Fu, J Kipnis - Neuron, 2018 - cell.com
The nature of fluid dynamics within the brain parenchyma is a focus of intensive research. Of
particular relevance is its participation in diseases associated with protein accumulation and …