[HTML][HTML] Multiplexed immunosensors for point-of-care diagnostic applications

BG Rosa, OE Akingbade, X Guo… - Biosensors and …, 2022 - Elsevier
Accurate, reliable, and cost-effective immunosensors are clinically important for the early
diagnosis and monitoring of progressive diseases, and multiplexed sensing is a promising …

Multiplexed immunosensors and immunoarrays

A Jones, L Dhanapala, RNT Kankanamage… - Analytical …, 2019 - ACS Publications
Immunoassays make use of highly specific antigen− antibody binding and provide sensitive
ways to detect a wide range of biomacromolecules, bacteria, viruses, and small molecules …

Highly Flexible Deep-Learning-Based Automatic Analysis for Graphically Encoded Hydrogel Microparticles

JH Choi, W Jang, YJ Lim, SJ Mun, KW Bong - ACS sensors, 2023 - ACS Publications
Graphically encoded hydrogel microparticle (HMP)-based bioassay is a diagnostic tool
characterized by exceptional multiplex detectability and robust sensitivity and specificity …

Pushing the detection limits: Strategies towards highly sensitive optical-based protein detection

N Momenbeitollahi, T Cloet, H Li - Analytical and Bioanalytical Chemistry, 2021 - Springer
Proteins are one of the main constituents of living cells. Studying the quantities of proteins
under physiological and pathological conditions can give valuable insights into health …

[HTML][HTML] Dielectrophoresis assisted high-throughput detection system for multiplexed immunoassays

SM Yang, Q Lin, H Zhang, R Yin, W Zhang… - Biosensors and …, 2021 - Elsevier
Digital ELISA is introduced as a novel platform with unique advantages for detecting multiple
kinds of single-molecule in the sample. How to improve the sensitivity of detection is the …

A platform for multiplexed colorimetric microRNA detection using shape-encoded hydrogel particles

N Juthani, PS Doyle - Analyst, 2020 - pubs.rsc.org
We report a platform utilizing a reporter enzyme, which produces a chromogenic indigo
precipitate that preferentially localizes within a hydrogel microparticle. The 3D network of the …

Discontinuous dewetting in a degassed mold for fabrication of homogeneous polymeric microparticles

HU Kim, YH Roh, SJ Mun, KW Bong - ACS Applied Materials & …, 2020 - ACS Publications
Discontinuous dewetting (DD) is an attractive technique that enables the production of large
liquid arrays in microwells and is applicable to the synthesis of anisotropic microparticles …

Microfluidic fabrication of encoded hydrogel microparticles for application in multiplex immunoassay

YH Roh, HJ Lee, KW Bong - BioChip Journal, 2019 - Springer
Recent interests in comprehensive protein surveys and protein biomarker studies have led
to an increased demand for simultaneous measurement of multiple proteins in a single …

Multiplex SNP Genotyping Using SWITCH: Sequence‐Specific Nanoparticle with Interpretative Toehold‐Mediated Sequence Decoding in Hydrogel

W Choi, E Park, S Bae, KH Choi, S Han, KH Son… - Small, 2022 - Wiley Online Library
Single nucleotide polymorphisms (SNPs) that can alter phenotypes of individuals play a
pivotal role in disease development and, more importantly, responses to therapy. However …

Precipitation-based colorimetric multiplex immunoassay in hydrogel particles

YH Roh, HJ Lee, JY Kim, HU Kim, SM Kim, KW Bong - Lab on a Chip, 2020 - pubs.rsc.org
Despite a growing demand for more accessible diagnostic technologies, current methods
struggle to simultaneously detect multiple analytes with acceptable sensitivity and portability …