Cancers represent complex ecosystems comprising tumor cells and a multitude of non-
cancerous cells, embedded in an altered extracellular matrix. The tumor microenvironment …

Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

Circulating tumor cells (CTCs) are the seeds of distant metastasis, and the number of CTCs
detected in the blood of cancer patients is associated with a worse prognosis. CTCs face …

The interaction of tumor cells with platelets is a prerequisite for successful hematogenous
metastatic dissemination. Upon tumor cell arrival in the blood, tumor cells immediately …

Primary tumors actively and specifically prime pre-metastatic niches (PMNs), the future sites
of organotropic metastasis, preparing these distant microenvironments for disseminated …

The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Platelets exhibit distinct surface moieties responsible for modulating their adhesion to
various disease‐relevant substrates involving vascular damage, immune evasion, and …

The development of cell membrane-modified biomimetic nanoparticles has extensively
increased during the past years due to their exceptional biocompatibility, evasion from the …

Surgical removal of malignant tumors is a mainstay in controlling most solid cancers.
However, surgical insult also increases the risk of tumor recurrence and metastasis. Tissue …

Platelets are small anucleate cellular fragments that are released by megakaryocytes and
safeguard vascular integrity through a process termed 'haemostasis'. However, platelets …