Dark classics in chemical neuroscience: 3, 4-methylenedioxymethamphetamine
LE Dunlap, AM Andrews, DE Olson - ACS chemical neuroscience, 2018 - ACS Publications
Better known as “ecstasy”, 3, 4-methylenedioxymethamphetamine (MDMA) is a small
molecule that has played a prominent role in defining the ethos of today's teenagers and …
molecule that has played a prominent role in defining the ethos of today's teenagers and …
A proposed mechanism for the MDMA-mediated extinction of traumatic memories in PTSD patients treated with MDMA-assisted therapy
RJ Sottile, T Vida - Frontiers in psychiatry, 2022 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a devastating psychiatric disorder afflicting millions
of people around the world. Characterized by severe anxiety, intrusive thoughts, pervasive …
of people around the world. Characterized by severe anxiety, intrusive thoughts, pervasive …
Distinct neural mechanisms for the prosocial and rewarding properties of MDMA
BD Heifets, JS Salgado, MD Taylor… - Science translational …, 2019 - science.org
The extensively abused recreational drug (±) 3, 4-methylenedioxymethamphetamine
(MDMA) has shown promise as an adjunct to psychotherapy for treatment-resistant …
(MDMA) has shown promise as an adjunct to psychotherapy for treatment-resistant …
Systemic enhancement of serotonin signaling reverses social deficits in multiple mouse models for ASD
JJ Walsh, P Llorach, DF Cardozo Pinto… - …, 2021 - nature.com
Autism spectrum disorder (ASD) is a common set of heterogeneous neurodevelopmental
disorders resulting from a variety of genetic and environmental risk factors. A core feature of …
disorders resulting from a variety of genetic and environmental risk factors. A core feature of …
Using conditioned place preference to identify relapse prevention medications
TC Napier, AA Herrold, H De Wit - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Stimuli, including contexts, which predict the availability or onset of a drug effect, can acquire
conditioned incentive motivational properties. These conditioned properties endure after …
conditioned incentive motivational properties. These conditioned properties endure after …
The neurochemistry of social reward during development: What have we learned from rodent models?
A Manduca, E Carbone, S Schiavi… - Journal of …, 2021 - Wiley Online Library
Social rewards are fundamental to survival and overall health. Several studies suggest that
adequate social stimuli during early life are critical for developing appropriate …
adequate social stimuli during early life are critical for developing appropriate …
Dopamine D1 and D3 receptor polypharmacology as a potential treatment approach for substance use disorder
E Galaj, S Ewing, R Ranaldi - Neuroscience & Biobehavioral Reviews, 2018 - Elsevier
In the search for efficacious pharmacotherapies to treat cocaine addiction much attention
has been given to agents targeting dopamine D1 or D3 receptors because of the …
has been given to agents targeting dopamine D1 or D3 receptors because of the …
Dose and time-dependent selective neurotoxicity induced by mephedrone in mice
Mephedrone is a drug of abuse marketed as 'bath salts". There are discrepancies
concerning its long-term effects. We have investigated the neurotoxicity of mephedrone in …
concerning its long-term effects. We have investigated the neurotoxicity of mephedrone in …
Mephedrone and MDMA: a comparative review
J Mead, A Parrott - Brain research, 2020 - Elsevier
Mephedrone and MDMA are both constituents of party drugs, with mephedrone being
relatively new compared to MDMA. This review compares current knowledge regarding the …
relatively new compared to MDMA. This review compares current knowledge regarding the …
Neuronal changes and oxidative stress in adolescent rats after repeated exposure to mephedrone
R López-Arnau, J Martínez-Clemente, T Rodrigo… - Toxicology and applied …, 2015 - Elsevier
Mephedrone is a new designer drug of abuse. We have investigated the neurochemical/
enzymatic changes after mephedrone administration to adolescent rats (3× 25 mg/kg, sc in a …
enzymatic changes after mephedrone administration to adolescent rats (3× 25 mg/kg, sc in a …